Intracellular Signaling

Cell signaling (cell signalling in British English) is part of any communication process that governs basic activities of cells and coordinates all cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis. Errors in signaling interactions and cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated more effectively and, theoretically, artificial tissues may be created.

Intracellular Signaling Products Targets

Products for Intracellular Signaling - Page 56

Cat.No. Product Name Information/Activity
BCC8051 WH-4-023 WH-4-023 is a potent and selective dual Lck/Src inhibitor with IC50 of 2 nM/6 nM for Lck and Src kinase respectively; little inhibition on p38α and KDR.
BCC6232 MLR 1023 Tolimidone is a potent and selective allosteric activator of Lyn kinase with an EC50 of 63 nM.
BCC5855 N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide 190078-50-3
BCC5853 N-Acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu 159439-02-8
BCC5914 ER 27319 maleate 1204480-26-1
BCC3799 Nilvadipine Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM.
BCC8085 c-JUN peptide 610273-01-3
BCC3607 SR 11302 160162-42-5
BCC1050 10058-F4 10058-F4 is a c-Myc inhibitor that prevents c-Myc-Max dimerization and transactivation of c-Myc target gene expression.
BCC7109 NSC 95397 NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor (Ki=32 nM (Cdc25A), 96 nM (Cdc25B), 40 nM (Cdc25C); IC50=22.3 nM (human Cdc25A), 56.9 nM (human Cdc25C), 125 nM (Cdc25B)). NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway.