Cancer Research
Cancer is a term used to define a group of diseases in which abnormal cells divide without control, are able to invade neighboring tissues/organs and metastasize. Cancer has been characterized by six hallmarks; self sufficiency in proliferative growth signals, insensitivity to growth inhibitors, evasion of apoptosis, limitless replicative potential, ability to develop blood vessels (angiogenesis), and tissue invasion and metastasis.
Cancer Research Products Areas
Products for Cancer Research - Page 60
- Cat.No. Product Name Information/Activity
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BCC7723
W146
W146 is a selective antagonist of sphingosine-1-phosphate receptor 1 (S1PR1) with an EC50 value of 398 nM.
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BCC7780
Cl-4AS-1
188589-66-4
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BCN2193
Testosterone
58-22-0
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BCC2481
Bicalutamide
Bicalutamide is a non-steroidal androgen receptor inhibitor.
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BCC4364
Flutamide
Flutamide is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.
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BCC7811
PF 998425
1076225-27-8
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BCC6069
TFM-4AS-1
188589-61-9
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BCC1333
AIM-100
AIM-100 is a small molecule inhibitor of Ack1 with an IC50 of 24 nM
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BCC2491
Finasteride
Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM).
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BCC4070
GSK 650394
GSK 650394 is a novel SGK inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively. GSK 650394 also inhibits influenza virus replication.
