Sibiricose A6CAS# 241125-75-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 241125-75-7 | SDF | Download SDF |
| PubChem ID | 6326021 | Appearance | Light yellow powder |
| Formula | C23H32O15 | M.Wt | 548.5 |
| Type of Compound | Phenylpropanoids | Storage | Desiccate at -20°C |
| Synonyms | 3-O-Sinapoylsucrose | ||
| Solubility | Soluble in DMSO and methan | ||
| Chemical Name | [(2S,3S,4R,5R)-4-hydroxy-2,5-bis(hydroxymethyl)-2-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxolan-3-yl] (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate | ||
| SMILES | COC1=CC(=CC(=C1O)OC)C=CC(=O)OC2C(C(OC2(CO)OC3C(C(C(C(O3)CO)O)O)O)CO)O | ||
| Standard InChIKey | WTCVROXOIQEIRC-IBVGEFGBSA-N | ||
| Standard InChI | InChI=1S/C23H32O15/c1-33-11-5-10(6-12(34-2)16(11)28)3-4-15(27)36-21-18(30)14(8-25)37-23(21,9-26)38-22-20(32)19(31)17(29)13(7-24)35-22/h3-6,13-14,17-22,24-26,28-32H,7-9H2,1-2H3/b4-3+/t13-,14-,17-,18-,19+,20-,21+,22-,23+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Sibiricose A6 displays antidepressant-like action, it may prevent or relieve depression; it also shows potent antioxidant activity. |
| In vitro | Study on antidepressant components of sucrose ester from Polygala tenuifolia[Reference: WebLink]《China Journal of Chinese Materia Medica》 2008-11To investigate the antidepressant components of Polygala tenuifolia. Indirect identification of antioxidants in Polygalae Radix through their reaction with 2,2-diphenyl-1-picrylhydrazyl and subsequent HPLC-ESI-Q-TOF-MS/MS.[Pubmed: 26452897]Talanta. 2015 Nov 1;144:830-5.A rapid and efficient method for the identification of antioxidants in the traditional Chinese medicine Polygalae Radix (PR) by HPLC-ESI-Q-TOF-MS/MS is described. |
| In vivo | Absorbable phenylpropenoyl sucroses from Polygala tenuifolia.[Pubmed: 21716172]Molecules. 2011 Jun 29;16(7):5507-13.
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Sibiricose A6 Dilution Calculator
Sibiricose A6 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.8232 mL | 9.1158 mL | 18.2315 mL | 36.4631 mL | 45.5789 mL |
| 5 mM | 0.3646 mL | 1.8232 mL | 3.6463 mL | 7.2926 mL | 9.1158 mL |
| 10 mM | 0.1823 mL | 0.9116 mL | 1.8232 mL | 3.6463 mL | 4.5579 mL |
| 50 mM | 0.0365 mL | 0.1823 mL | 0.3646 mL | 0.7293 mL | 0.9116 mL |
| 100 mM | 0.0182 mL | 0.0912 mL | 0.1823 mL | 0.3646 mL | 0.4558 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Absorbable phenylpropenoyl sucroses from Polygala tenuifolia.[Pubmed:21716172]
Molecules. 2011 Jun 29;16(7):5507-13.
Three phenylpropenoyl sucroses--sibiricose A5, A6 and 3',6-disinapoyl sucrose--were isolated from the 30% EtOH extract of Polygala tenuifolia, which displayed antidepressant-like action. HPLC analysis indicated that the three phenylpropenoyl sucroses could be absorbed into serum. From the serum pharmacochemistry point of view, these three phenylpropenoyl sucroses might prevent or relieve depression.
Indirect identification of antioxidants in Polygalae Radix through their reaction with 2,2-diphenyl-1-picrylhydrazyl and subsequent HPLC-ESI-Q-TOF-MS/MS.[Pubmed:26452897]
Talanta. 2015 Nov 1;144:830-5.
A rapid and efficient method for the identification of antioxidants in the traditional Chinese medicine Polygalae Radix (PR) by HPLC-ESI-Q-TOF-MS/MS is described. The method is based on the hypothesis that upon reaction of antioxidants with 1,1-diphenyl-2-picrylhydrazyl (DPPH), the peak areas of compounds with potential antioxidant activities in the HPLC chromatogram will be significantly reduced in comparison to the untreated sample. The identity confirmation was achieved by Q-TOF-MS/MS technique. With this method, eight components were proposed possessing potent antioxidant activity. They were identified as sibiricose A5, Sibiricose A6, sucrose monoester, polygalaxanthone III, tenuifoliside B, 3',6-disinapoylsucrose (DISS), sucrose diester, tenuifoliside C, respectively. DISS was proposed to be the most potent one. The antioxidant activity of DISS was evaluated by DPPH, ABTS radical scavenging assay and ferric-reducing antioxidant power (FRAP) assay in vitro. Vitamin C (Vc) was used as positive control substance. DISS showed moderate DPPH (DISS's IC50 value was 1024.17 mug/mL, Vc's was 294.68 mug/mL) and ABTS (IC50 324.13 mug/mL, Vc's was 117.50 mug/mL) free radical scavenging capacity and ferric-reducing antioxidant power. DISS can be used as a new source of natural antioxidant in foods and cosmetics.
