Griffithazanone ACAS# 240122-30-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 240122-30-9 | SDF | Download SDF |
| PubChem ID | 10706277 | Appearance | Yellow powder |
| Formula | C14H11NO4 | M.Wt | 257.2 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (3R,4R)-3-hydroxy-4-methyl-3,4-dihydro-1H-benzo[g]quinoline-2,5,10-trione | ||
| SMILES | CC1C(C(=O)NC2=C1C(=O)C3=CC=CC=C3C2=O)O | ||
| Standard InChIKey | SZPJSZDUSLSXDF-KSBSHMNSSA-N | ||
| Standard InChI | InChI=1S/C14H11NO4/c1-6-9-10(15-14(19)11(6)16)13(18)8-5-3-2-4-7(8)12(9)17/h2-6,11,16H,1H3,(H,15,19)/t6-,11-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| In vitro | A new cytotoxic 1-azaanthraquinone from the stems of Goniothalamus laoticus.[Pubmed: 20554005]Fitoterapia. 2010 Oct;81(7):894-6.
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| Structure Identification | Chem Pharm Bull (Tokyo). 2006 Jul;54(7):1040-3.New constituents from stems of Goniothalamus amuyon.[Pubmed: 16819228]
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Griffithazanone A Dilution Calculator
Griffithazanone A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.888 mL | 19.4401 mL | 38.8802 mL | 77.7605 mL | 97.2006 mL |
| 5 mM | 0.7776 mL | 3.888 mL | 7.776 mL | 15.5521 mL | 19.4401 mL |
| 10 mM | 0.3888 mL | 1.944 mL | 3.888 mL | 7.776 mL | 9.7201 mL |
| 50 mM | 0.0778 mL | 0.3888 mL | 0.7776 mL | 1.5552 mL | 1.944 mL |
| 100 mM | 0.0389 mL | 0.1944 mL | 0.3888 mL | 0.7776 mL | 0.972 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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New constituents from stems of Goniothalamus amuyon.[Pubmed:16819228]
Chem Pharm Bull (Tokyo). 2006 Jul;54(7):1040-3.
Two new compounds, goniothalesacetate (1) and goniothalesdiol A (2) together with goniodiol-7-monoacetate, goniodiol-8-monoacetate, leiocarpin C, liriodenine, Griffithazanone A, 4-methyl-2,9,10-(2H)-1-azaanthracencetrione, velutinam and aristolactam BII were isolated and characterized from the stems of Goniothalamus amuyon. Structures of new compounds were determined by spectral analysis.
A new cytotoxic 1-azaanthraquinone from the stems of Goniothalamus laoticus.[Pubmed:20554005]
Fitoterapia. 2010 Oct;81(7):894-6.
A new 1-azaanthraquinone, named laoticuzanone A (1), and a synthetically known 3-methyl-1H-1-azaanthracene-2,9,10-trione (2), together with four known compounds, Griffithazanone A (3), methyl sinapate (4), methyl p-coumarate (5), and p-hydroxyphenylethyl p-coumarate (6) were isolated from the stems of Goniothalamus laoticus. Their structures were established on the basis of spectroscopic data as well as comparisons with the previous literature data. Compound 1 showed the highest cytotoxicity against KB and HeLa cells with IC(50) values of 0.68 and 0.50 mug/ml, respectively.
