Saikosaponin I

CAS# 103629-71-6

Saikosaponin I

Catalog No. BCN8605----Order now to get a substantial discount!

Product Name & Size Price Stock
Saikosaponin I: 5mg Please Inquire In Stock
Saikosaponin I: 10mg Please Inquire In Stock
Saikosaponin I: 20mg Please Inquire Please Inquire
Saikosaponin I: 50mg Please Inquire Please Inquire
Saikosaponin I: 100mg Please Inquire Please Inquire
Saikosaponin I: 200mg Please Inquire Please Inquire
Saikosaponin I: 500mg Please Inquire Please Inquire
Saikosaponin I: 1000mg Please Inquire Please Inquire

Quality Control of Saikosaponin I

Number of papers citing our products

Chemical structure

Saikosaponin I

3D structure

Chemical Properties of Saikosaponin I

Cas No. 103629-71-6 SDF Download SDF
PubChem ID 21636282 Appearance Powder
Formula C48H78O17 M.Wt 927.13
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4R,5R,6S)-2-[(2R,3S,4R,5R,6R)-6-[[(3S,4aR,6aS,6bR,8S,8aS,12aS,14bS)-8-hydroxy-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a-dodecahydropicen-3-yl]oxy]-4,5-dihydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
SMILES CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3CCC4(C(C3(C)C)CCC5(C4=CC=C6C5(CC(C7(C6CC(CC7)(C)C)CO)O)C)C)C)COC8C(C(C(C(O8)CO)O)O)O)O)O)O
Standard InChIKey CMCKJNVAUXCQCZ-FRCIMGCNSA-N
Standard InChI InChI=1S/C48H78O17/c1-22-31(52)33(54)37(58)41(61-22)65-39-26(20-60-40-36(57)34(55)32(53)25(19-49)62-40)63-42(38(59)35(39)56)64-30-12-13-45(6)27(44(30,4)5)11-14-46(7)28(45)10-9-23-24-17-43(2,3)15-16-48(24,21-50)29(51)18-47(23,46)8/h9-10,22,24-27,29-42,49-59H,11-21H2,1-8H3/t22-,24-,25+,26+,27-,29-,30-,31-,32+,33+,34-,35+,36+,37+,38+,39+,40+,41-,42-,45-,46+,47+,48+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Saikosaponin I

The herbs of Bupleurum chinense DC.

Biological Activity of Saikosaponin I

DescriptionSaikosaponin I shows strong inhibition activity against influenza virus WSN33.
TargetsAntifection

Protocol of Saikosaponin I

Structure Identification
China Journal of Chinese Materia Medica, 2016, 41(7):1251.

Triterpenoid saponins from Bupleurum marginatum var. stenophyllum.[Pubmed: 28879740]


METHODS AND RESULTS:
Twelve compounds were obtained by phytochemical investigation of 70% EtOH ( containing 0.5%NH3•H2O )extract of the roots of Bupleurum marginatum var. stenophyllum. Based on comparison of their spectral data, including HR-ESI-MS, ¹H-NMR, ¹³C-NMR data, with those of the literature, their structures were elucidated as saikosaponin b2 (1), saikosaponin a(2), saikosaponin b1(3), saikosaponin d (4), hydroxysaikosaponin a (5), saikosaponin b3 (6), saikosaponin c(7),Saikosaponin I(8), saikosaponin f (9), chikusaikosides Ⅱ(10), saikosaponin s (11), and Saikosaponin I(12).
CONCLUSIONS:
All compounds belong to olean-type triterpenoid saponin and compounds 1, 3, 5, 8-9,11, and 12 were isolated from this plant for the first time. At a concentration of 20 μmol•L⁻¹, compounds 2, 4, 6, 8, 11 and 12 showed strong inhibition activity against influenza virus WSN33 with the inhibition rate of 91.3%,88.6%,53.4%,61.3%,77.3% and 57.4%,respectively.

Saikosaponin I Dilution Calculator

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Saikosaponin I Molarity Calculator

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Preparing Stock Solutions of Saikosaponin I

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0786 mL 5.393 mL 10.786 mL 21.5719 mL 26.9649 mL
5 mM 0.2157 mL 1.0786 mL 2.1572 mL 4.3144 mL 5.393 mL
10 mM 0.1079 mL 0.5393 mL 1.0786 mL 2.1572 mL 2.6965 mL
50 mM 0.0216 mL 0.1079 mL 0.2157 mL 0.4314 mL 0.5393 mL
100 mM 0.0108 mL 0.0539 mL 0.1079 mL 0.2157 mL 0.2696 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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