Oxprenolol hydrochlorideCAS# 6452-73-9 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 6452-73-9 | SDF | Download SDF |
| PubChem ID | 71172 | Appearance | Powder |
| Formula | C15H24ClNO3 | M.Wt | 301.81 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble to 100 mM in sterile water | ||
| Chemical Name | 1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)propan-2-ol;hydrochloride | ||
| SMILES | CC(C)NCC(COC1=CC=CC=C1OCC=C)O.Cl | ||
| Standard InChIKey | COAJXCLTPGGDAJ-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C15H23NO3.ClH/c1-4-9-18-14-7-5-6-8-15(14)19-11-13(17)10-16-12(2)3;/h4-8,12-13,16-17H,1,9-11H2,2-3H3;1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Non-selective β-adrenergic antagonist. |
Oxprenolol hydrochloride Dilution Calculator
Oxprenolol hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.3133 mL | 16.5667 mL | 33.1334 mL | 66.2669 mL | 82.8336 mL |
| 5 mM | 0.6627 mL | 3.3133 mL | 6.6267 mL | 13.2534 mL | 16.5667 mL |
| 10 mM | 0.3313 mL | 1.6567 mL | 3.3133 mL | 6.6267 mL | 8.2834 mL |
| 50 mM | 0.0663 mL | 0.3313 mL | 0.6627 mL | 1.3253 mL | 1.6567 mL |
| 100 mM | 0.0331 mL | 0.1657 mL | 0.3313 mL | 0.6627 mL | 0.8283 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Spectrophotometric determination of oxprenolol hydrochloride as its Fe (III) complex.[Pubmed:2400517]
Farmaco. 1990 Apr;45(4):447-53.
A spectrophotometric determination of Oxprenolol hydrochloride in pharmaceutical preparations is described. The method is based on the reaction of Oxprenolol hydrochloride with Fe (III) ion in the presence of ammonium thiocyanate, in acid media. The complex formed between Oxprenolol hydrochloride and Fe (III) ion was extracted with chloroform and assayed spectrophometrically at 477 nm. The results obtained are reproducible and hence the method is suitable for the determination of Oxprenolol hydrochloride in pharmaceutical dosage forms.
Zero-order release formulation of oxprenolol hydrochloride with swelling and erosion control.[Pubmed:2748519]
Pharm Res. 1989 Apr;6(4):313-7.
Zero-order release of Oxprenolol hydrochloride was obtained by controlling the swelling and erosion of the matrix. This formulation involves only mixing of drug, hydroxypropylmethylcellulose (HPMC), and sodium carboxymethylcellulose (Na CMC) at the ratio of 1:0.4:1.6, respectively, and compressing the mixture directly into tablets. The in vitro release pattern from this optimized matrix tablet was reproducible. Accelerated stability studies revealed that the optimized formulation remains stable for an approximately 2-year shelf life. This sustained-release (SR) tablet was evaluated in dogs, and for comparison a conventional (CV) formulation was also given at the same dose level. Plasma oxprenolol levels were monitored by a sensitive and specific high-performance liquid chromatographic (HPLC) method. Significant differences in the pharmacokinetic parameters, i.e., lower Cmax, higher values of tmax, MRT, AUC, and plasma concentration at 24 hr, and nearly constant plasma levels over 12 hr, indicated that the SR matrix tablet is superior to the CV rapid-releasing formulation. The in vitro release parameters and in vivo pharmacokinetics correlated well.
Microdetermination of oxprenolol hydrochloride and metoprolol tartrate with ammonium metavanadate.[Pubmed:18964300]
Talanta. 1987 Feb;34(2):296-8.
A micro method has been developed for the determination of Oxprenolol hydrochloride and metoprolol tartrate in pure form and in pharmaceutical preparations, with vanadium(V) in acidic medium.
