NG,NG-Dimethylarginine dihydrochlorideCAS# 220805-22-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 220805-22-1 | SDF | Download SDF |
| PubChem ID | 16219246 | Appearance | Colorless cryst. |
| Formula | C8H20Cl2N4O2 | M.Wt | 275.18 |
| Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S)-2-amino-5-[[amino(dimethylamino)methylidene]amino]pentanoic acid;dihydrochloride | ||
| SMILES | CN(C)C(=NCCCC(C(=O)O)N)N.Cl.Cl | ||
| Standard InChIKey | SYLNVYJOPZWPJI-ILKKLZGPSA-N | ||
| Standard InChI | InChI=1S/C8H18N4O2.2ClH/c1-12(2)8(10)11-5-3-4-6(9)7(13)14;;/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14);2*1H/t6-;;/m0../s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. NG,NG-Dimethylarginine dihydrochloride is a reversible inhibitor of nitric oxide synthetase in vivo and in vitro. |
| Targets | NO |
NG,NG-Dimethylarginine dihydrochloride Dilution Calculator
NG,NG-Dimethylarginine dihydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.634 mL | 18.1699 mL | 36.3399 mL | 72.6797 mL | 90.8496 mL |
| 5 mM | 0.7268 mL | 3.634 mL | 7.268 mL | 14.5359 mL | 18.1699 mL |
| 10 mM | 0.3634 mL | 1.817 mL | 3.634 mL | 7.268 mL | 9.085 mL |
| 50 mM | 0.0727 mL | 0.3634 mL | 0.7268 mL | 1.4536 mL | 1.817 mL |
| 100 mM | 0.0363 mL | 0.1817 mL | 0.3634 mL | 0.7268 mL | 0.9085 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Aminopurvalanol A
Catalog No.:BCC7249
CAS No.:220792-57-4
- Aquifoliunine E-III
Catalog No.:BCN3096
CAS No.:220751-20-2
- Curlignan
Catalog No.:BCN3977
CAS No.:220736-54-9
- Ketoprofen
Catalog No.:BCC4430
CAS No.:22071-15-4
- Oxonic acid potassium salt
Catalog No.:BCC4165
CAS No.:2207-75-2
- Antisauvagine-30
Catalog No.:BCC5868
CAS No.:220673-95-0
- RJR-2403 oxalate
Catalog No.:BCC1902
CAS No.:220662-95-3
- Tigecycline
Catalog No.:BCC2499
CAS No.:220620-09-7
- GB 1a
Catalog No.:BCN7237
CAS No.:220611-41-6
- Diphyllin
Catalog No.:BCN8066
CAS No.:22055-22-7
- Caspase-3/7 Inhibitor I
Catalog No.:BCC1140
CAS No.:220509-74-0
- 1-Methyl-2-pentyl-4(1H)-quinolinone
Catalog No.:BCN4943
CAS No.:22048-98-2
New Products
- 7-Methoxy-8-Hydroxy-4-Methylcoumarin
Catalog No.:BCC8291
CAS No.:22084-94-2
- Thunalbene
Catalog No.:BCN3688
CAS No.:220862-05-5
- 2,3-O-Isopropylidenyl euscaphic acid
Catalog No.:BCN4944
CAS No.:220880-90-0
- GW5074
Catalog No.:BCC4391
CAS No.:220904-83-6
- 13-O-Cinnamoylbaccatin III
Catalog No.:BCN7344
CAS No.:220932-65-0
- 13-O-Deacetyltaxumairol Z
Catalog No.:BCN4945
CAS No.:220935-39-7
- Antalarmin hydrochloride
Catalog No.:BCC7480
CAS No.:220953-69-5
- Lumiracoxib
Catalog No.:BCC4440
CAS No.:220991-20-8
- Guaiacol glycidyl ether
Catalog No.:BCC8992
CAS No.:2210-74-4
- 1''-Methoxyerythrinin C
Catalog No.:BCN3966
CAS No.:221002-11-5
- 1alpha,4beta,10beta-Trihydroxyguaia-2,11(13)-dien-12,6alpha-olide
Catalog No.:BCN7483
CAS No.:221148-94-3
- Erysubin A
Catalog No.:BCN4946
CAS No.:221150-18-1
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure.[Pubmed:1347093]
Lancet. 1992 Mar 7;339(8793):572-5.
Nitric oxide (NO), synthesised from L-arginine, contributes to the regulation of blood pressure and to host defence. We describe in-vitro and in-vivo evidence that NO synthesis can be inhibited by an endogenous compound, NG,NG-dimethylarginine (asymmetrical dimethylarginine, ADMA). In man, this inhibitor is found in plasma and more than 10 mg is excreted in urine over 24 h. However, in patients with end-stage chronic renal failure, who have little or no urine output, elimination is blocked and circulating concentrations of the inhibitor rise sufficiently to inhibit NO synthesis. Accumulation of endogenous ADMA, leading to impaired NO synthesis, might contribute to the hypertension and immune dysfunction associated with chronic renal failure.
NG,NG-Dimethylarginine dihydrochloride,220805-22-1,Natural Products, buy NG,NG-Dimethylarginine dihydrochloride , NG,NG-Dimethylarginine dihydrochloride supplier , purchase NG,NG-Dimethylarginine dihydrochloride , NG,NG-Dimethylarginine dihydrochloride cost , NG,NG-Dimethylarginine dihydrochloride manufacturer , order NG,NG-Dimethylarginine dihydrochloride , high purity NG,NG-Dimethylarginine dihydrochloride
