IsoacetovanilloneCAS# 6100-74-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 6100-74-9 | SDF | Download SDF |
| PubChem ID | 95693 | Appearance | Powder |
| Formula | C9H10O3 | M.Wt | 166.17 |
| Type of Compound | Phenols | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1-(3-hydroxy-4-methoxyphenyl)ethanone | ||
| SMILES | CC(=O)C1=CC(=C(C=C1)OC)O | ||
| Standard InChIKey | YLTGFGDODHXMFB-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C9H10O3/c1-6(10)7-3-4-9(12-2)8(11)5-7/h3-5,11H,1-2H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Isoacetovanillone shows anti-inflammatory potential. |
| Targets | Immunology & Inflammation related |
| In vivo | Anti-inflammatory effect of Pycnocycla spinosa extract and its component isoacetovanillone on acetic acid induced colitis in rats.[Pubmed: 26600861 ]Res Pharm Sci. 2015 Jul-Aug;10(4):345-55.Colitis is an inflammatory disease of the intestine with unknown etiology involving multiple immune, genetic and environmental factors. We were interested to examine the effect of total extract from Pycnocycla spinosa Boiss. on the treatment of experimental colitis. Mediators involved in colonic inflammation are prostaglandins, interleukins, leukotriene as well as an increase in myeloperoxidase (MPO) activity.
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Isoacetovanillone Dilution Calculator
Isoacetovanillone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 6.0179 mL | 30.0897 mL | 60.1793 mL | 120.3587 mL | 150.4483 mL |
| 5 mM | 1.2036 mL | 6.0179 mL | 12.0359 mL | 24.0717 mL | 30.0897 mL |
| 10 mM | 0.6018 mL | 3.009 mL | 6.0179 mL | 12.0359 mL | 15.0448 mL |
| 50 mM | 0.1204 mL | 0.6018 mL | 1.2036 mL | 2.4072 mL | 3.009 mL |
| 100 mM | 0.0602 mL | 0.3009 mL | 0.6018 mL | 1.2036 mL | 1.5045 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Anti-inflammatory effect of Pycnocycla spinosa extract and its component isoacetovanillone on acetic acid induced colitis in rats.[Pubmed:26600861]
Res Pharm Sci. 2015 Jul-Aug;10(4):345-55.
Colitis is an inflammatory disease of the intestine with unknown etiology involving multiple immune, genetic and environmental factors. We were interested to examine the effect of total extract from Pycnocycla spinosa Boiss. on the treatment of experimental colitis. Mediators involved in colonic inflammation are prostaglandins, interleukins, leukotriene as well as an increase in myeloperoxidase (MPO) activity. Therefore, MPO activity was also determined in this research. P. spinosa hydroalcoholic extract (5, 10 and 20 mg/kg) or Isoacetovanillone (2, 5 and 10 mg/kg) were administered orally, started 2 h before induction of colitis by intrarectal administration of acetic acid (3%) in rats. Prednisolone (4 m/kg) was used as the standard drug for comparison. Biochemical evaluation of inflamed colon was done using assay of MPO activity. After 5 days treatments, mucosal ulceration was evaluated. Intrarectal instillation of acetic acid caused significant inflammatory reactions as indicated by macroscopic and microscopic changes. The activity of MPO increased in vehicle treated groups while recovered to normal level by pretreatment of animals with P. spinosa extract, Isoacetovanillone and prednisolone. P. spinosa and Isoacetovanillone-treated groups showed significantly lower score values of macroscopic and microscopic characters when compared with the vehicle treated negative control group. The beneficial effect of P. spinosa was comparable with that of prednisolone. This research has shown the anti-inflammatory potential of P. spinosa extract and Isoacetovanillone in experimentally induced colitis.
