Cimigenol-3-oneCAS# 31222-32-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 31222-32-9 | SDF | Download SDF |
| PubChem ID | 90471440 | Appearance | Powder |
| Formula | C30H46O5 | M.Wt | 486.69 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1CC2C(OC3(C1C4(CCC56CC57CCC(=O)C(C7CCC6C4(C3O)C)(C)C)C)O2)C(C)(C)O | ||
| Standard InChIKey | JFTOWADKDXNJHZ-OTEZEVKPSA-N | ||
| Standard InChI | InChI=1S/C30H46O5/c1-16-14-17-22(25(4,5)33)35-30(34-17)21(16)26(6)12-13-29-15-28(29)11-10-20(31)24(2,3)18(28)8-9-19(29)27(26,7)23(30)32/h16-19,21-23,32-33H,8-15H2,1-7H3/t16-,17-,18+,19+,21-,22+,23-,26-,27-,28-,29+,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Cimigenol-3-one is a natural product from Calophyllum inophyllum. |
| Structure Identification | Journal of Yunnan University of Traditional Chinese Medicine, 2013, 36 (3) :31-35.Studies on Chemical Constituents of the Rhizomes of Cimicifuga dahurica.[Reference: WebLink]To study the major chemical constituents of the rhizomes of C.dahurica. |
Cimigenol-3-one Dilution Calculator
Cimigenol-3-one Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0547 mL | 10.2735 mL | 20.547 mL | 41.0939 mL | 51.3674 mL |
| 5 mM | 0.4109 mL | 2.0547 mL | 4.1094 mL | 8.2188 mL | 10.2735 mL |
| 10 mM | 0.2055 mL | 1.0273 mL | 2.0547 mL | 4.1094 mL | 5.1367 mL |
| 50 mM | 0.0411 mL | 0.2055 mL | 0.4109 mL | 0.8219 mL | 1.0273 mL |
| 100 mM | 0.0205 mL | 0.1027 mL | 0.2055 mL | 0.4109 mL | 0.5137 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Eucalyptin
Catalog No.:BCN5227
CAS No.:3122-88-1
- Sideroxylin
Catalog No.:BCN5226
CAS No.:3122-87-0
- H-D-Ser-OH
Catalog No.:BCC2676
CAS No.:312-84-5
- Methylionene
Catalog No.:BCN7120
CAS No.:31197-54-3
- Sudan II
Catalog No.:BCN8383
CAS No.:3118-97-6
- D-Xylose
Catalog No.:BCC8320
CAS No.:31178-70-8
- SYM 2081
Catalog No.:BCC6840
CAS No.:31137-74-3
- RFRP 3 (human)
Catalog No.:BCC6261
CAS No.:311309-27-0
- 3-Methyl-4-nitrobenzoic acid
Catalog No.:BCN2261
CAS No.:3113-71-1
- Taxifolin 3'-O-glucoside
Catalog No.:BCN6808
CAS No.:31106-05-5
- Benzoquinonium dibromide
Catalog No.:BCC6641
CAS No.:311-09-1
- 5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavanone
Catalog No.:BCN1461
CAS No.:310888-07-4
- IQ 3
Catalog No.:BCC8093
CAS No.:312538-03-7
- Tetrahydrocannabivarin
Catalog No.:BCN6935
CAS No.:31262-37-0
- SKI II
Catalog No.:BCC5029
CAS No.:312636-16-1
- THIQ
Catalog No.:BCC7539
CAS No.:312637-48-2
- gamma-Mangostin
Catalog No.:BCN5228
CAS No.:31271-07-5
- Indacaterol
Catalog No.:BCC1650
CAS No.:312753-06-3
- Hygromycin B
Catalog No.:BCC1204
CAS No.:31282-04-9
- Raucaffricine
Catalog No.:BCN4653
CAS No.:31282-07-2
- TCS JNK 5a
Catalog No.:BCC5148
CAS No.:312917-14-9
- LDN-27219
Catalog No.:BCC6236
CAS No.:312946-37-5
- Arjunic acid
Catalog No.:BCN5229
CAS No.:31298-06-3
- Estradiol Cypionate
Catalog No.:BCC4477
CAS No.:313-06-4
Studies on the constituents of Cimicifuga foetida collected in Guizhou Province and their cytotoxic activities.[Pubmed:22689393]
Chem Pharm Bull (Tokyo). 2012;60(5):571-7.
Two new triterpenoids and a chromone glycoside, namely, 24-epi-Cimigenol-3-one (1), foetinoside (2), cimifugin-4'-O-[6''-feruloyl]-beta-D-glucopyranoside (3), together with 18 known compounds, were isolated from the rhizomes of Cimicifuga foetida L. collected in Guizhou Province, China. All of the compounds were identified by spectroscopic methods, as well as chemical methods. In the in vitro cytotoxicity evaluation of these compounds against 5 human cancer cell lines, cimigenol (8) exerted the most potent cytotoxic activity against SMMC-7721 (7.87 microM) and A-549 (12.16 microM), while cimiacerin B (9) also showed obvious cytotoxicity against the A-549 cell line, with an IC(50) value of 16.77 microM.
