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Chrysophanol 1-glucoside

CAS# 4839-60-5

Chrysophanol 1-glucoside

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Chrysophanol 1-glucoside:5mg Please Inquire In Stock
Chrysophanol 1-glucoside:10mg Please Inquire In Stock
Chrysophanol 1-glucoside:20mg Please Inquire In Stock
Chrysophanol 1-glucoside:50mg Please Inquire In Stock

Quality Control of Chrysophanol 1-glucoside

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Chemical structure

Chrysophanol 1-glucoside

3D structure

Chemical Properties of Chrysophanol 1-glucoside

Cas No. 4839-60-5 SDF Download SDF
PubChem ID 6324923 Appearance Powder
Formula C21H20O9 M.Wt 416.4
Type of Compound Anthraquinones Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 8-hydroxy-3-methyl-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyanthracene-9,10-dione
SMILES CC1=CC(=C2C(=C1)C(=O)C3=C(C2=O)C(=CC=C3)O)OC4C(C(C(C(O4)CO)O)O)O
Standard InChIKey QKPDYSSHOSPOKH-JNHRPPPUSA-N
Standard InChI InChI=1S/C21H20O9/c1-8-5-10-15(18(26)14-9(16(10)24)3-2-4-11(14)23)12(6-8)29-21-20(28)19(27)17(25)13(7-22)30-21/h2-6,13,17,19-23,25,27-28H,7H2,1H3/t13-,17-,19+,20-,21-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Chrysophanol 1-glucoside

The roots of Rheum emodi

Protocol of Chrysophanol 1-glucoside

Structure Identification
Zhong Yao Cai. 2016 Jul;39(7):1578-81.

The Effect in Extraction of Different Ratio of Dahuang-Taoren for Ten Kinds of Chemical Constituents from Rhizoma Rhei.[Pubmed: 30204362]

To investigate the effect of Dahuang-Taoren with different proportion of extraction amount changes of ten kinds of chemical constituents in Rhizoma Rhei.
METHODS AND RESULTS:
Uniform method to set different ratio( 1∶ 5,2∶ 5,2∶ 3,1∶ 1,3∶ 2,5∶ 2,5∶ 1),and set the control group ( Dahuang-Taoren( 1 ∶ 0). HPLC was used to determine the content of ten constituents as gallic acid,( +)-catechin,sennoside B,anthraquinones( aloe-emodin,rhein,emodin,chrysophanol,physcion,Chrysophanol 1-O-glucoside,emodin major grape glycoside) in different ratio of drug. Different proportions of Dahuang-Taoren on the extraction amount of ten chemical components in Rhizoma Rhei changes were analyzed. . Compared to the control group, Dahuang-Taoren with different ratio( 5∶ 1,5∶ 2,3∶ 2) in a sample with increasing proportion of Taoren,the extraction amount of ten kinds of constituents of Rhizoma Rhei gradually decreased;Dahuang-Taoren with ratio of 1∶ 1,ten kinds of constituents in extraction of total amount arrived minimum value. Dahuang-Taoren with different ratio( 2∶ 3,2∶ 5,1∶ 5) in a sample with increasing proportion of Taoren,the extraction amount of gallic acid,( +) catechin,chrysophanol of Rhizoma Rhei increased significantly.
CONCLUSIONS:
There is obvious change in chemical constituents of the extraction amount of Rhizoma Rhei with the change of the ratio in Dahuang-Taoren, and Dahuang-Taoren with the ratio( 2∶ 3,2∶ 5,1∶ 5),the extraction amount of gallic acid,( +)-catechin,sennoside B,aloe-emodin,emodin,chrysophanol,physcion,chrysophanol-1-O-glucoside are significantly higher than control group.

Chrysophanol 1-glucoside Dilution Calculator

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Chrysophanol 1-glucoside Molarity Calculator

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Preparing Stock Solutions of Chrysophanol 1-glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4015 mL 12.0077 mL 24.0154 mL 48.0307 mL 60.0384 mL
5 mM 0.4803 mL 2.4015 mL 4.8031 mL 9.6061 mL 12.0077 mL
10 mM 0.2402 mL 1.2008 mL 2.4015 mL 4.8031 mL 6.0038 mL
50 mM 0.048 mL 0.2402 mL 0.4803 mL 0.9606 mL 1.2008 mL
100 mM 0.024 mL 0.1201 mL 0.2402 mL 0.4803 mL 0.6004 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Chrysophanol 1-glucoside

[Study on correlation of soil nutrients and content of active constituents in root of Rumex gmelini].[Pubmed:18161286]

Zhongguo Zhong Yao Za Zhi. 2007 Oct;32(19):1984-7.

OBJECTIVE: To provide scientific basis for the selection of agrotype and property fertilization for Rumex gmelini cultivated in compliance with good agricultural practice (GAP). METHOD: HPLC method was applied to determinate the content of seven active constituents (resveratrol, polydatin, Chrysophanol 1-glucoside, nepodin, emodin, chrysophanol and physcion) of annual R. gmelini. And the correlation between soil nutrients and content of active constituents in the root of R. gmelini were analyzed by stepwise regression analysis. RESULT: Seven regression equation were established. The statistic significance was found in three of them. CONCLUSION: The soil with high total K level is not suitable for R. gmelini cultivation. But the higher available N, available P, available K level of soil is suitable.

[Study on the optimal harvesting time of Rumex gmelini by analyzing the contents of principal components].[Pubmed:16110856]

Zhongguo Zhong Yao Za Zhi. 2005 Jun;30(11):808-11.

OBJECTIVE: To establish a method used for optimization of harvesting time and determine the best time for harvesting Rumex gmelini. METHOD: An HPLC method was applied to determinate the contents of seven active constituents(resveratrol, polydatin, Chrysophanol 1-glucoside, nepodin, emodin, chrysophanol and physcion)of R. gmelini at different development stage. The result was analyzed by principal component analysis. RESULT: The accumulation of active constituents showed a regular pattern. CONCLUSION: The best harvesting time of R. gmelini is early July.

Description

Chrysophanein is a chrysophanol glycoside from leaves and roots of Aloe hijazensis. Chrysophanein shows a moderate cytotoxic activity against several carcinoma cells lines.

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