(+)-Catechin hydrateCAS# 225937-10-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 225937-10-0 | SDF | Download SDF |
| PubChem ID | 107957 | Appearance | Powder |
| Formula | C15H16O7 | M.Wt | 308.28 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | DMSO : 150 mg/mL (Need ultrasonic and warming) | ||
| Chemical Name | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol;hydrate | ||
| SMILES | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O.O | ||
| Standard InChIKey | OFUMQWOJBVNKLR-NQQJLSKUSA-N | ||
| Standard InChI | InChI=1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | (+)-Catechin hydrate has antioxidant activity and is effective in reducing oxidative stress. (+)-Catechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. |
| Targets | COX-1 |
| In vivo | Effect of (+)-catechin hydrate on oxidative stress induced by high sucrose and high fat diet in male Wistar rats.[Pubmed: 24266106]Indian J Exp Biol. 2013 Oct;51(10):823-7.
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(+)-Catechin hydrate Dilution Calculator
(+)-Catechin hydrate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.2438 mL | 16.219 mL | 32.438 mL | 64.8761 mL | 81.0951 mL |
| 5 mM | 0.6488 mL | 3.2438 mL | 6.4876 mL | 12.9752 mL | 16.219 mL |
| 10 mM | 0.3244 mL | 1.6219 mL | 3.2438 mL | 6.4876 mL | 8.1095 mL |
| 50 mM | 0.0649 mL | 0.3244 mL | 0.6488 mL | 1.2975 mL | 1.6219 mL |
| 100 mM | 0.0324 mL | 0.1622 mL | 0.3244 mL | 0.6488 mL | 0.811 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Effect of (+)-catechin hydrate on oxidative stress induced by high sucrose and high fat diet in male Wistar rats.[Pubmed:24266106]
Indian J Exp Biol. 2013 Oct;51(10):823-7.
Increased lipid peroxidation and reduced glutathione levels in liver of rats fed high sucrose high fat (HSHF) diet were normalized by concomitant administration of (+)-Catechin hydrate. Plasma non-enzymatic antioxidants viz. alpha-tocopherol, ascorbic acid and total thiols decrease were also significantly less in rats administered with (+)-Catechin hydrate concomitantly with HSHF diet. Thus the present results indicate that (+)-Catechin hydrate has antioxidant activity and is effective in reducing oxidative stress. The study is of clinical importance as oxidative stress is known to be the cause of many clinical manifestations viz. cancer, Parkinson's disease, atherosclerosis, heart failure, myocardial infarction and many other diseases.
