Bromhexine hydrochlorideCAS# 611-75-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 611-75-6 | SDF | Download SDF |
| PubChem ID | 5702220 | Appearance | Powder |
| Formula | C14H21Br2ClN2 | M.Wt | 412.6 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : 20 mg/mL (48.47 mM; Need ultrasonic) H2O : 3.33 mg/mL (8.07 mM; Need ultrasonic) | ||
| Chemical Name | 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline;hydrochloride | ||
| SMILES | CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2.Cl | ||
| Standard InChIKey | UCDKONUHZNTQPY-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C14H20Br2N2.ClH/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)17;/h7-8,12H,2-6,9,17H2,1H3;1H | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Bromhexine hydrochloride Dilution Calculator
Bromhexine hydrochloride Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4237 mL | 12.1183 mL | 24.2365 mL | 48.4731 mL | 60.5914 mL |
| 5 mM | 0.4847 mL | 2.4237 mL | 4.8473 mL | 9.6946 mL | 12.1183 mL |
| 10 mM | 0.2424 mL | 1.2118 mL | 2.4237 mL | 4.8473 mL | 6.0591 mL |
| 50 mM | 0.0485 mL | 0.2424 mL | 0.4847 mL | 0.9695 mL | 1.2118 mL |
| 100 mM | 0.0242 mL | 0.1212 mL | 0.2424 mL | 0.4847 mL | 0.6059 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Bromhexine Hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm. Target: Others Bromhexine is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine has antioxidant properties. Bromhexine is intended to support the body's mechanisms for clearing mucus from the respiratory tract. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport. From Wikipedia. [1]
References:
[1]. http://en.wikipedia.org/wiki/Bromhexine
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Sensitive determination of bromhexine hydrochloride based on its quenching effect on luminol/H2 O2 electrochemiluminescence system.[Pubmed:29605968]
Luminescence. 2018 Jun;33(4):698-703.
In this paper, the electrochemiluminescence (ECL) behavior of luminol/H2 O2 system in the presence of Bromhexine hydrochloride (BrH) was investigated. It was found that the ECL intensity of luminol/H2 O2 system on a platinum electrode could be intensely quenched by BrH owing to the scavenging superoxide radical ability of BrH, and therefore the sensitive determination of BrH was possible. Under optimal conditions, the quenched ECL intensity was linear to the concentration of BrH in a wide range of 0.08 to 500 muM, with a detection limit of 0.02 muM (signal-to-noise ratio (S/N) = 3). This ECL method possessed the merits of rapid, simple and sensitive, and was successfully applied to the BrH quantification in pharmaceutical preparations with satisfactory recoveries of 91.0 +/- 4.0 to 106.5 +/- 3.4%. The possible route of the quenched ECL of luminol/H2 O2 in the presence of BrH was also discussed.
