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Abieta-8,11,13-triene-7,15,18-triol

CAS# 337527-10-3

Abieta-8,11,13-triene-7,15,18-triol

Catalog No. BCN5262----Order now to get a substantial discount!

Product Name & Size Price Stock
Abieta-8,11,13-triene-7,15,18-triol:5mg Please Inquire In Stock
Abieta-8,11,13-triene-7,15,18-triol:10mg Please Inquire In Stock
Abieta-8,11,13-triene-7,15,18-triol:20mg Please Inquire In Stock
Abieta-8,11,13-triene-7,15,18-triol:50mg Please Inquire In Stock

Quality Control of Abieta-8,11,13-triene-7,15,18-triol

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Chemical structure

Abieta-8,11,13-triene-7,15,18-triol

3D structure

Chemical Properties of Abieta-8,11,13-triene-7,15,18-triol

Cas No. 337527-10-3 SDF Download SDF
PubChem ID 91895315 Appearance Powder
Formula C20H30O3 M.Wt 318.5
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,4aS,9R,10aR)-1-(hydroxymethyl)-7-(2-hydroxypropan-2-yl)-1,4a-dimethyl-2,3,4,9,10,10a-hexahydrophenanthren-9-ol
SMILES CC1(CCCC2(C1CC(C3=C2C=CC(=C3)C(C)(C)O)O)C)CO
Standard InChIKey FTCCXIDYXDLLRK-LCLWPZTBSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Abieta-8,11,13-triene-7,15,18-triol

The barks of Pinus yunnanensis

Biological Activity of Abieta-8,11,13-triene-7,15,18-triol

Description1. Abieta-8,11,13-triene-7alpha,15,18-triol,7alpha,8alpha,13beta,14beta-diepoxyabietan-18-oic acid, and 18-nor-abieta-8,11,13-triene-4alpha,7alpha,15-triol may have inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), they may as a primary screening for antitumor promotors.

Abieta-8,11,13-triene-7,15,18-triol Dilution Calculator

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Preparing Stock Solutions of Abieta-8,11,13-triene-7,15,18-triol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1397 mL 15.6986 mL 31.3972 mL 62.7943 mL 78.4929 mL
5 mM 0.6279 mL 3.1397 mL 6.2794 mL 12.5589 mL 15.6986 mL
10 mM 0.314 mL 1.5699 mL 3.1397 mL 6.2794 mL 7.8493 mL
50 mM 0.0628 mL 0.314 mL 0.6279 mL 1.2559 mL 1.5699 mL
100 mM 0.0314 mL 0.157 mL 0.314 mL 0.6279 mL 0.7849 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Abieta-8,11,13-triene-7,15,18-triol

Abietane diterpenoids from the cones of Larix kaempferi and their inhibitory effects on Epstein-Barr virus activation.[Pubmed:11270723]

Planta Med. 2001 Feb;67(1):55-60.

Four known (1-3, 8) and four new abietane diterpenes, 15-hydroxy-8alpha,14alpha,12alpha,13alpha-diepoxyabietan-18-oic acid (4), 7alpha,8alpha,13beta,14beta-diepoxyabietan-18-oic acid (5), 18-nor-abieta-8,11,13-triene-4alpha,7alpha,15-triol (6), and abieta-8,11,13-triene-7alpha,15,18-triol (7) were isolated from the CHCl3 extract of the cones of Larix koempferi. A known compound, 13,14-seco-13,14-dioxoabiet-13-en-18-oic acid (8) was isolated from natural sources for the first time. Their structures were determined by chemical and spectroscopic methods including 1D and 2D NMR techniques. The absolute stereostructure of 5 was determined by X-ray crystallographic analysis. The inhibitory effects of these compounds on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate (TPA), were examined as a primary screening for antitumor promotors.

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