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8-Hydroxyapigenin

CAS# 41440-05-5

8-Hydroxyapigenin

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Product Name & Size Price Stock
8-Hydroxyapigenin:5mg Please Inquire In Stock
8-Hydroxyapigenin:10mg Please Inquire In Stock
8-Hydroxyapigenin:20mg Please Inquire In Stock
8-Hydroxyapigenin:50mg Please Inquire In Stock

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Chemical structure

8-Hydroxyapigenin

3D structure

Chemical Properties of 8-Hydroxyapigenin

Cas No. 41440-05-5 SDF Download SDF
PubChem ID 5281665 Appearance Yellow crystalline powder
Formula C15H10O6 M.Wt 286.239
Type of Compound N/A Storage Desiccate at -20°C
Synonyms Isoscutellarein
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5,7,8-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=C(C=C3O)O)O)O
Standard InChIKey NXHQVROAKYDSNW-UHFFFAOYSA-N
Standard InChI InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)12-6-10(18)13-9(17)5-11(19)14(20)15(13)21-12/h1-6,16-17,19-20H
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

8-Hydroxyapigenin Dilution Calculator

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8-Hydroxyapigenin Molarity Calculator

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Preparing Stock Solutions of 8-Hydroxyapigenin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4936 mL 17.4679 mL 34.9358 mL 69.8717 mL 87.3396 mL
5 mM 0.6987 mL 3.4936 mL 6.9872 mL 13.9743 mL 17.4679 mL
10 mM 0.3494 mL 1.7468 mL 3.4936 mL 6.9872 mL 8.734 mL
50 mM 0.0699 mL 0.3494 mL 0.6987 mL 1.3974 mL 1.7468 mL
100 mM 0.0349 mL 0.1747 mL 0.3494 mL 0.6987 mL 0.8734 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 8-Hydroxyapigenin

Virtual Screening of Indonesian Herbal Database as HIV-1 Protease Inhibitor.[Pubmed:24616554]

Bioinformation. 2014 Feb 19;10(2):52-5.

HIV-1 (Human immunodeficiency virus type 1)s infection is considered as one of most harmful disease known by human, the survivability rate of the host reduced significantly when it developed into AIDS. HIV drug resistance is one of the main problems of its treatment and several drug designs have been done to find new leads compound as the cure. In this study, in silico virtual screening approach was used to find lead molecules from the library or database of natural compounds as HIV-1 protease inhibitor. Virtual screening against Indonesian Herbal Database with AutoDock was performed on HIV-1 protease. From the virtual screening, top ten compounds obtained were 8-Hydroxyapigenin 8-(2",4"-disulfatoglucuronide), Isoscutellarein 4'-methyl ether, Amaranthin, Torvanol A, Ursonic acid, 5-Carboxypyranocyanidin 3-O-(6"-O-malonyl-beta-glucopyranoside), Oleoside, Jacoumaric acid, Platanic acid and 5-Carboxypyranocyanidin 3-O-beta-glucopyranoside.

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