4-Epi-curcumenol

CAS# 350602-21-0

4-Epi-curcumenol

Catalog No. BCN3523----Order now to get a substantial discount!

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4-Epi-curcumenol:5mg Please Inquire In Stock
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4-Epi-curcumenol:20mg Please Inquire In Stock
4-Epi-curcumenol:50mg Please Inquire In Stock
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Quality Control of 4-Epi-curcumenol

Number of papers citing our products

Chemical structure

4-Epi-curcumenol

3D structure

Chemical Properties of 4-Epi-curcumenol

Cas No. 350602-21-0 SDF Download SDF
PubChem ID 11128245 Appearance Powder
Formula C15H22O2 M.Wt 234.3
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1CCC2C13CC(=C(C)C)C(O3)(C=C2C)O
Standard InChIKey ISFMXVMWEWLJGJ-PAPYEOQZSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 4-Epi-curcumenol

The rhizomes of Curcuma zedoaria

Biological Activity of 4-Epi-curcumenol

DescriptionStandard reference
In vitro

Inhibitors of Nitric Oxide Production and New Sesquiterpenes, 4-epi-Curcumenol, Neocurcumenol, Gajutsulactones A and B, and Zedoarolides A and B from Zedoariae Rhizoma.[Reference: WebLink]

Heterocycles.2001 May; 55(5).


METHODS AND RESULTS:
Six new guaiane- or secoguaiane-type sesquiterpenes, 4-Epi-curcumenol, neocurcumenol, gajutsulactones A and B, and zedoarolides A and B, were isolated from aqueous acetone extract of Zedoariae Rhizoma (Zingiberaceae), together with 34 sesquiterpenes and two diarylheptanoids. The stereostructures of new sesquiterpenes were elucidated on the basis of chemical and physicochemical evidence, which included nuclear Overhauser effect (NOE) and circular dichroic (CD) spectroscopic analyses.
CONCLUSIONS:
Gajutsulactones A and B, and 14 sesquiterpenes, and two diarylheptanoids were found to inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-activated mouse peritoneal macrophages.

4-Epi-curcumenol Dilution Calculator

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4-Epi-curcumenol Molarity Calculator

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Preparing Stock Solutions of 4-Epi-curcumenol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.268 mL 21.3402 mL 42.6803 mL 85.3606 mL 106.7008 mL
5 mM 0.8536 mL 4.268 mL 8.5361 mL 17.0721 mL 21.3402 mL
10 mM 0.4268 mL 2.134 mL 4.268 mL 8.5361 mL 10.6701 mL
50 mM 0.0854 mL 0.4268 mL 0.8536 mL 1.7072 mL 2.134 mL
100 mM 0.0427 mL 0.2134 mL 0.4268 mL 0.8536 mL 1.067 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on 4-Epi-curcumenol

Inhibitors of Nitric Oxide Production and New Sesquiterpenes, 4-epi-Curcumenol, Neocurcumenol, Gajutsulactones A and B, and Zedoarolides A and B from Zedoariae Rhizoma.

Heterocycles.2001 May; 55(5).

Six new guaiane- or secoguaiane-type sesquiterpenes, 4-Epi-curcumenol, neocurcumenol, gajutsulactones A and B, and zedoarolides A and B, were isolated from aqueous acetone extract of Zedoariae Rhizoma (Zingiberaceae), together with 34 sesquiterpenes and two diarylheptanoids. The stereostructures of new sesquiterpenes were elucidated on the basis of chemical and physicochemical evidence, which included nuclear Overhauser effect (NOE) and circular dichroic (CD) spectroscopic analyses. Gajutsulactones A and B, and 14 sesquiterpenes, and two diarylheptanoids were found to inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-activated mouse peritoneal macrophages.

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