1-OctacosanolCAS# 557-61-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 557-61-9 | SDF | Download SDF |
| PubChem ID | 68406 | Appearance | Oil |
| Formula | C28H58O | M.Wt | 410.76 |
| Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
| Synonyms | n-Octacosanol, Octacosyl alcohol, Octanosol, Montanyl alcohol, Cluytyl alcoho | ||
| Solubility | DMSO : < 1 mg/mL (insoluble or slightly soluble) Ethanol : < 1 mg/mL (insoluble) *1-Octacosanol is usually formulated as a suspension. | ||
| Chemical Name | octacosan-1-ol | ||
| SMILES | CCCCCCCCCCCCCCCCCCCCCCCCCCCCO | ||
| Standard InChIKey | CNNRPFQICPFDPO-UHFFFAOYSA-N | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1-Octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory properties, cytoprotective use, and ergogenic properties, it is used as a nutritional supplement. |
| Targets | Antifection |
| In vitro | Antioxidant, Antibacterial, and Cytotoxic Activities of the Ethanolic Origanum vulgare Extract and Its Major Constituents.[Pubmed: 27051475]Oxid Med Cell Longev. 2016;2016:1404505.Oregano is a perennial shrub that grows in the mountains of the Mediterranean and Euro/Irano-Siberian regions. |
| Kinase Assay | Xanthine oxidase inhibitors from Archidendron clypearia (Jack.) I.C. Nielsen: Results from systematic screening of Vietnamese medicinal plants.[Pubmed: 28756918 ]Asian Pac J Trop Med. 2017 Jun;10(6):549-556.To screen Vietnamese medicinal plants for xanthine oxidase (XO) inhibitory activity and to isolate XO inhibitor(s) from the most active plant.
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1-Octacosanol Dilution Calculator
1-Octacosanol Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4345 mL | 12.1726 mL | 24.3451 mL | 48.6902 mL | 60.8628 mL |
| 5 mM | 0.4869 mL | 2.4345 mL | 4.869 mL | 9.738 mL | 12.1726 mL |
| 10 mM | 0.2435 mL | 1.2173 mL | 2.4345 mL | 4.869 mL | 6.0863 mL |
| 50 mM | 0.0487 mL | 0.2435 mL | 0.4869 mL | 0.9738 mL | 1.2173 mL |
| 100 mM | 0.0243 mL | 0.1217 mL | 0.2435 mL | 0.4869 mL | 0.6086 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Xanthine oxidase inhibitors from Archidendron clypearia (Jack.) I.C. Nielsen: Results from systematic screening of Vietnamese medicinal plants.[Pubmed:28756918]
Asian Pac J Trop Med. 2017 Jun;10(6):549-556.
OBJECTIVE: To screen Vietnamese medicinal plants for xanthine oxidase (XO) inhibitory activity and to isolate XO inhibitor(s) from the most active plant. METHODS: The plants materials were extracted by methanol. The active plant materials were fractionated using different organic solvents, including n-hexane, ethyl acetate, and n-butanol. Bioassay-guided fractionation and column chromatography were used to isolate compounds. The compounds structures were elucidated by analysis of spectroscopic data, including IR, MS, and NMR. RESULTS: Three hundreds and eleven methanol extracts (CME) belonging to 301 Vietnamese herbs were screened for XO inhibitory activity. Among these plants, 57 extracts displayed XO inhibitory activity at 100 mug/mL with inhibition rates of over 50%. The extracts of Archidendron clypearia (A. clypearia), Smilax poilanei, Linociera ramiflora and Passiflora foetida exhibited the greatest potency with IC50 values below 30 mug/mL. Chemical study performed on the extract of A. clypearia resulted in the isolation of six compounds, including 1-Octacosanol, docosenoic acid, daucosterol, methyl gallate, quercitrin and (-)-7-O-galloyltricetiflavan. The compound (-)-7-O-galloyltricetiflavan showed the most potent XO inhibitory activity with an IC50 value of 25.5 mumol/L. CONCLUSIONS: From this investigation, four Vietnamese medicinal plants were identified to have XO inhibitory effects with IC50 values of the methanol extracts below 30 mug/mL. Compound (-)-7-O- galloyltricetiflavan was identified as an XO inhibitor from A. clypearia with IC50 value of 25.5 mumol/L.
