BCN5116Excavatin MBotanical source: The barks of Clausena excavata(CAS NO.:250293-31-3)
BCN2637PhellopterinPhellopterin is a natural product isolated from P. trifoliata. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.(CAS NO.:2543-94-4)
BCN65407-Methoxy-4-methylcoumarin4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 μg/ml and 13.47 μg/ml.(CAS NO.:2555-28-4)
BCN5015ByakangelicolByakangelicol, isolated from Angelica dahurica, inhibits interleukin-1beta (IL-1beta) -induced prostaglandin E2 (PGE2) release in A549 cells mediated by suppression of cyclooxygenase-2 (COX-2) expression and the activity of COX-2 enzyme. Byakangelicol has therapeutic potential as an anti-inflammatory drug on airway inflammation.(CAS NO.:26091-79-2)
BCN2698Oxypeucedanin hydrateOxypeucedanin hydrate ((+)-Oxypeucedanin hydrate) is a natural product isolated from D. anethifolia. Prangol exhibits mild toxicity on fibroblasts and parental lymphoma cells.(CAS NO.:2643-85-8)
BCN1228(+)-UlopterolBotanical source: The roots of Peucedanum praeruptorum Dunn(CAS NO.:28095-18-3)
BCN5180TomentinBotanical source: The barks of Jatropha curcas(CAS NO.:28449-62-9)
BCN51817-Geranyloxy-6-methoxycoumarin7-O-Geranylscopoletin is a coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, paralysis, antispasmodic, stimulant and hemiplegia.(CAS NO.:28587-43-1)
BCN5187HeracleninHeraclenin, a natural furanocoumarin, isolated from the root parts of the plant Prangos pabularia. Heraclenin significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT).(CAS NO.:2880-49-1)
BCN5205XanthotoxinMethoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight.(CAS NO.:298-81-7)
BCN59056,7-DihydroxycoumarinEsculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities.(CAS NO.:305-01-1)
BCN52215'-DemethylaquillochinBotanical source: The herbs of Mallotus apelta(CAS NO.:305364-91-4)
BCN2766IsodemethylwedelolactonIsodemethylwedelolactone is a kind of procoagulant and haemolytic constituent isolated from Eclipta alba.(CAS NO.:350681-33-3)
BCN6792Isopropylidenylacetyl-marmesinIsopropylidenylacetyl-marmesin ((±)-Prantschimgin) is a coumarin isolated from the roots of F. bracteata.(CAS NO.:35178-20-2)
BCN5288NeobyakangelicolBotanical source: The roots of Angelica dahurica(CAS NO.:35214-82-5)
BCN6789AlloisoimperatorinBotanical source: The bark of Clausena lansium(CAS NO.:35214-83-6)
