Products with Neuroprotection Bioactivity

Explore BioCrick products associated with Neuroprotection biological activity, including catalog numbers, product names and available bioactivity information.

Cat. No.	Product Name
BCN3820	Stearic Acid
Stearic Acid and its derivatives have been used as gelators in food and pharmaceutical gel formulations. Stearic Acid is a potent phosphatase 1B inhibitor, possibly causing an enhancement in the insulin receptor signaling to stimulate glucose uptake into adipocytes. Stearic Acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes, it also can reduce metastatic tumor burden.
BCN3825	2,5-Dihydroxyacetophenone
2,5-Dihydroxyacetophenone is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity, it possesses anti-inflammatoryanti-anxiety, and neuroprotective qualities. 2,5-Dihydroxyacetophenone treatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells.
BCN3830	Incensole acetate
Incensole acetate is a novel anti-inflammatory compound that inhibits NF-κB activation. Incensole acetate has protective effects on cerebral ischemic injury, it can reduce depressive-like behavior and modulate hippocampal BDNF and CRF expression of submissive animals.
BCN3832	Vanillyl alcohol
Vanillyl alcohol possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit the cytotoxicity and improved cell viability in 1-methyl-4-phenylpyridinium (MPP+)-induced MN9D dopaminergic cells, it also can attenuate the elevation of reactive oxygen species (ROS) levels, decrease in the Bax/Bcl-2 ratio and poly (ADP-ribose) polymerase proteolysis.
BCN3833	Panaxynol
Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation. Panaxynol has neuroprotective, and anti-proliferative effects, it induces neurite outgrowth in PC12D cells via cAMP- and MAP kinase-dependent mechanisms, and protects cortical neurons from ischemia-like injury by up-regulation of HIF-1alpha expression and inhibition of apoptotic cascade. Panaxynol has inhibitory effects on the proliferation of human pancreatic cancer cell PANC-1through inhibiting cell division and down-regulating Ki67 expression.

Neuroprotection Bioactivity Products