Products with Antiangiogenic bioactivity

Cat.No. Product Name
BCN3684 Zerumin A
1. Zerumin A inhibits the proliferation and migration steps, to prevent angiogenesis progress.
BCN3832 Vanillyl alcohol
Vanillyl alcohol possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit the cytotoxicity and improved cell viability in 1-methyl-4-phenylpyridinium (MPP+)-induced MN9D dopaminergic cells, it also can attenuate the elevation of reactive oxygen species (ROS) levels, decrease in the Bax/Bcl-2 ratio and poly (ADP-ribose) polymerase proteolysis.
BCN4045 Lupiwighteone
1. Lupiwighteone has anti-angiogenesis potential . 2. Lupiwighteone has anticancer and cancer preventive effects on SH-SY5Y cells.
BCN4154 4-Hydroxybenzyl alcohol
4-Hydroxybenzyl alcohol possesses anti-angiogenic, anti-inflammatory and anti- nociceptive activity possibly via its down-regulating activity on NO production, which may be partly responsible for the pharmacological efficacy of several folkloric medicines. It exhibits beneficial effects in cerebral ischemic injury, has neuroprotective effect through upregulation of Nrf2, Prdx6, and PDI expression via the PI3K/Akt pathway.
BCN4171 Wogonin
Wogonin is an inhibitor of CDK9, which has anti-inflammatory and anti-tumor activities, it could be developed into an efficient natural sensitizer for resistant human myelogenous leukemia. It has a wide spectrum of targets including PGE2, NO, Nrf2, Src, MEK1/2, ERK1/2, NFκB,MLCK, MLC.

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