Products with Antiangiogenic bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2724 | Tetrahydrocurcumin |
| Tetrahydrocurcumin can inhibit tumor angiogenesis, treat human breast cancer,and be a promising candidate for the prevention of CIPN by chemotherapeutic agents.Tetrahydrocurcumin exhibits protective effects against cisplatin-induced oxidative renal damage in rats by inhibiting cyclooxygenase-2 and caspase-3 activation; it has a protective effect over arsenic induced toxicity in rat. | |
| BCN2892 | (2S)-Isoxanthohumol |
| 1. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic properties, seems to regulate in vivo vascular proliferation and stabilization and the EC-VSMC-inflammatory crosstalk. | |
| BCN2927 | Dehydroeffusol |
| 1. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. 2. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity, it is a potential drug candidate for anti-gastric cancer neovascularization and anti-gastric cancer therapy. 3. Dehydroeffusol may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. 4. Dehydroeffusol possesses anxiolytic and sedative properties and does not affect the general movement coordination of mice. 5. Dehydroeffusol displays enhanced antimicrobial activities in light, its antimicrobial activities (minimum inhibitory concentrations) against methicillin-resistant and -sensitive Staphylococcus aureus and Candida albicans are increased 16 fold by irradiation with ultraviolet A (UVA). | |
| BCN2934 | Terrestrosin D |
| 1. Terrestrosin D can induce apoptotic cell death and inhibit angiogenesis in xenograft tumor cells, cell cycle arrest and induction of apoptosis in cancer cells and endothelial cells might be plausible mechanisms of actions for the observed antitumor and antiangiogenic activities of terrestrosin D. | |
| BCN2998 | 8-Prenylnaringenin |
| 8-Prenylnaringenin is a phytoestrogen with high estrogenic activity, it shows more potent effects on promoting osteoblastic bone formation and inhibiting osteoclastic bone resorption by ERα instead of ERβ than the two classic phytoestrogens: genistein and daidzein. 8-Prenylnaringenin at all assayed doses (0.001-20 µM) presumably improves mitochondrial function, whereas a high dose of XN (5 µM) worsens the functionality of this organelle. | |
