Products with Analgesia bioactivity

Cat.No. Product Name
BCN2175 Pregabalin
Pregabalin, a potent anticonvulsant agent, is used in treatment-resistant epileptic patients.Pregabalin (30 and 100mg/kg) presents central spinal but not central supraspinal antinociceptive effect and Pregabalin 100mg/kg shows peripheral antinociceptive effect. Pregabalin may be effective for the reduction of neuropathic pain, it improves postoperative analgesia compared with placebo at the expense of increased sedation and visual disturbances.
BCN2291 Diacerein
Diacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.The feasibility of targeted delivery of Diacerein to articular tissue using soluble polysaccharide chondroitin sulfate as the targeting vector, this approach has the potential to significantly increase anti-arthritic drug concentration in joints without leading to systemic toxicity.
BCN2300 Cucurbitacin E
Cucurbitacin E has prevention of neurodegeneration, it has potent anti-proliferative, antineoplastic, anti-inflammatory and analgesic actions, it also exhibits immunosuppressive effect by attenuating critical cytokine expression through down-regulating the NF-κB signaling pathway.
BCN2319 Ginkgetin
Ginkgetin is a good STAT3 inhibitor , which has anti-inflammatory, neuroprotective, anti-influenza virus and anti-fungal activities. Ginkgetin induces apoptosis in PC-3 cells via activation of caspase 3 and inhibition of survival genes as a potent chemotherapeutic agent for prostate cancer treatment.
BCN2326 beta-Isosparteine
Sparteine is a class 1a antiarrhythmic agent, a sodium channel blocker. The deficient debrisoquine hydroxylation of Sparteine is due to the absence of P-450IID1 protein in the livers of poor metabolizers.

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