Neurotransmission

Neurotransmission, or synaptic transmission, involves the passage of signals by electrical or chemical means from one neuron to another. It allows communication between nerve cells for the propagation of electrical impulses to and from the central nervous system leading to the co-ordination of secretion, muscle contraction and organ function.

Neurotransmission Products Targets

Products for Neurotransmission - Page 80

Cat.No. Product Name Information/Activity
BCC7442 WAY 213613 WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM EAAT2. It displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3.8 μM, respectively). WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function.
BCC7168 ALX 5407 hydrochloride Selective non-transportable GlyT1 inhibitor
BCC7069 N-Arachidonylglycine 179113-91-8
BCC7677 LY 2365109 hydrochloride 868265-28-5
BCC7845 Org 24598 lithium salt 722456-08-8
BCC6288 Org 25543 hydrochloride Potent and selective GlyT2 inhibitor
BCN2744 Sarcosine Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site.
BCC2291 Cilostazol Cilostazol (OPC 13013) is a potent and selective inhibitor of phosphodiesterase (PDE) 3A, the isoform of PDE 3 in the cardiovascular system, with an IC50 of 0.2 μM.
BCC6271 Decynium 22 977-96-8
BCC6660 Dilazep dihydrochloride Dilazep dihydrochloride is an inhibitor of adenosine uptake. Dilazep dihydrochloride has cerebral and coronary vasodilating action through enhancement of effect of adenosine. Dilazep dihydrochloride also inhibits the ischemic damage, platelet aggregation, and membrane transport of nucleosides.