Neurotransmission

Neurotransmission, or synaptic transmission, involves the passage of signals by electrical or chemical means from one neuron to another. It allows communication between nerve cells for the propagation of electrical impulses to and from the central nervous system leading to the co-ordination of secretion, muscle contraction and organ function.

Neurotransmission Products Targets

Products for Neurotransmission - Page 16

Cat.No. Product Name Information/Activity
BCC4053 VU0152100 VU0152100 is a potent and selective allosteric potentiator of M4 mAChR with an EC50 of 380 ± 93 nM.
BCC7729 VU 0238429 VU 0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5), with an EC50 of 1.16 μM.
BCC6164 VU 0365114 VU 0365114 is a mAChR M5 positive allosteric modulator, with an EC50 of 2.7 μM.
BCC7705 3-Bromocytisine 3-Bromocytisine (3-Br-cytisine) is a potent nACh receptors agonist, with IC50s are 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7-nACh, respectively. 3-Bromocytisine (3-Br-cytisine) shows different effects on high (HS) and low (LS) ACh sensitivity α4β2 nAChRs with EC50s are 8 and 50 nM, respectively.
BCC7099 5-Iodo-A-85380 dihydrochloride 1217837-17-6
BCC7102 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative 213766-21-3
BCC3821 Nicotine Difartrate 65-31-6
BCC6118 3-pyr-Cytisine 948027-43-8
BCC1902 RJR-2403 oxalate Rivanicline oxalate (RJR-2403 oxalate; (E)-Metanicotine oxalate) is a neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki=26 nM); > 1,000 fold selectivity than α7 receptors(Ki= 3.6 μM).
BCC7975 SIB 1508Y maleate 192231-16-6