Neural Development

Neural development describes the growth and development of the nervous system starting from embryogenesis and continuing throughout life.

Neural Development Products Targets

Cat.No. Product Name Information/Activity
BCC5521 Emapunil Emapunil(AC-5216;XBD-173) is a translocator protein [TSPO (18 kDa)] ligand.
BCC7711 Bretazenil 84379-13-5
BCC6635 β-CCB 84454-35-3
BCC7162 CL 218872 66548-69-4
BCC6671 Dihydroergotoxine mesylate Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site.
BCC7560 DMCM hydrochloride DMCM hydrochloride is a nonselective full inverse agonist of benzodiazepine. DMCM shows bnding afinity at human recombinant GABAA αxβ3γ2 receptor subtypes with Kis of 10 nM, 13 nM, 7.5 nM, 2.2 nM for α1, α2, α3, and α5 receptors, respectively.
BCC6694 FG 7142 FG 7142 (ZK 39106; LSU-65), a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). FG 7142 (ZK 39106; LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 (ZK 39106; LSU-65) can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex.
BCC6738 FGIN-1-27 142720-24-9
BCC6739 FGIN-1-43 145040-29-5
BCC1259 Flumazenil Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.