Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.

Multiple Sclerosis Products Targets

Products for Multiple Sclerosis - Page 31

Cat.No. Product Name Information/Activity
BCC6597 (S)-(-)-5-Iodowillardiine 140187-25-3
BCC6572 Kainic acid Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.
BCC7297 MNI caged kainic acid 1315378-75-6
BCC6840 SYM 2081 SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively.
BCC7462 ACET 936095-50-0
BCC7275 NS 3763 70553-45-6
BCC2314 Topiramate Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase.
BCC7255 UBP 296 745055-86-1
BCC7172 UBP 301 569371-10-4
BCC7256 UBP 302 UBP 302 is a potent and selective GLUK5-subunit containing kainate receptor antagonist (apparent Kd=402 nM), and displays very little affinity on GluK2 (GluR6) kainate receptors. Anxiolytic effects.