Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 36

  1. Cat.No. Product Name Information/Activity
  2. BCC6631 Arcaine sulfate 14923-17-2 Arcaine sulfate chemical structure
  3. BCC6602 (R)-4-Carboxyphenylglycine 134052-68-9 (R)-4-Carboxyphenylglycine chemical structure
  4. BCC7078 CGP 37849 CGP 37849 is a potent, competitive and orally active N-methyl-D-aspartate (NMDA) receptor antagonist. CGP 37849 is an anticonvulsant in rodents and has antidepressant and anxiolytic-like effects. CGP 37849 chemical structure
  5. BCC7053 CGP 39551 127910-32-1 CGP 39551 chemical structure
  6. BCC7087 CGP 78608 hydrochloride CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). Anticonvulsant activity. CGP 78608 hydrochloride chemical structure
  7. BCC6986 CGS 19755 110347-85-8 CGS 19755 chemical structure
  8. BCC7757 7-Chlorokynurenic acid sodium salt 7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery. 7-Chlorokynurenic acid sodium salt chemical structure
  9. BCC6577 7-Chlorokynurenic acid 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery. 7-Chlorokynurenic acid chemical structure
  10. BCC6805 (2R,3S)-Chlorpheg 140924-23-8 (2R,3S)-Chlorpheg chemical structure
  11. BCC7369 Co 101244 hydrochloride 193356-17-1 Co 101244 hydrochloride chemical structure

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