Multiple Sclerosis
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.
Multiple Sclerosis Products Targets
- STAT (10)
- Voltage-gated Potassium (KV) Channel (38)
- Integrin Receptor (15)
- Others (29)
- Complement (2)
- Vitamin D Receptor (10)
- PORCN (4)
- beta-catenin (13)
- Casein Kinase 1 (7)
- AMPA Receptor (45)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- NMDA Receptor (87)
- Kainate Receptor (22)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- TRPM (8)
- Tankyrase (5)
- ROS and Other Gaseous Donor (8)
- Nrf2 (5)
- ITK (2)
- ASK1 (2)
- Acid-Sensing Ion Channel (3)
- Calcium-Activated Potassium (KCa) Channel (19)
- Inward Rectifier Potassium (Kir) Channel (21)
- NCX (5)
- Retinoid X Receptor (13)
- Cytokine (15)
Products for Multiple Sclerosis - Page 39
- Cat.No. Product Name Information/Activity
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BCC7619
Ro 61-8048
Ro 61-8048 is a potent and selective inhibitors of kynurenine hydroxylase with IC50 of 37 nM.
-
BCC7655
Ro 8-4304 hydrochloride
1312991-77-7
-
BCC6992
SDZ 220-040
174575-40-7
-
BCC1939
SDZ 220-581
SDZ 220-581 is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7.
-
BCC6730
Synthalin sulfate
182285-12-7
-
BCC6122
TCN 201
852918-02-6
-
BCC6123
TCN 213
556803-08-8
-
BCC6111
TCN 237 dihydrochloride
NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor.
-
BCC7482
TCS 46b
302799-86-6
-
BCC6984
CCMQ
132623-44-0
