Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune, inflammatory disease of the central nervous system (CNS), which causes damage to myelin and axons, resulting in neurological symptoms such as partial loss of sight, paresthesias and ataxia.

Multiple Sclerosis Products Targets

Products for Multiple Sclerosis - Page 17

Cat.No. Product Name Information/Activity
BCC5199 U-73122 U-73122 is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50of 1-2.1 µM for PLC.
BCC4950 Calcitriol Calcitriol is the most active metabolite of vitamin D and also a vitamin D receptor (VDR) agonist.
BCC4902 Doxercalciferol Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease.
BCC1944 Seocalcitol Seocalcitol is a vitamin D analog, binds vitamin D receptor protein from human osteosarcoma MG-63 cells with Kd of 0.27 nM.
BCC1556 Ercalcitriol Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.
BCC4962 Alfacalcidol Alfacalcidol (1-hydroxycholecalciferol) is a vitamin D active metabolites, acts as a non-selective VDR activator medication, and widely be used in the management of osteoporosis.
BCC4949 Calcifediol Calcifediol is a major circulating metabolite of vitamin D3, acting as a competitive inhibitor with an apparent Ki of 3.9 μM, suppresses PTH secretion and mRNA (ED50=2 nM).
BCC1444 Calcipotriol Calcipotriol is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
BCC1555 Ercalcidiol Ercalcidiol is a metabolite of vitamin D2, is regarded as an indicator of vitamin D nutritional status.
BCN2186 Vitamin D3 Cholecalciferol(Vitamin D3) is a naturally occuring form of vitamin D; Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells.