Immunology Research
Immunology is a branch of science that studies all aspects of the immune system, ranging from normal physiological functioning through to malfunctions which can lead to immunological diseases. Disorders that result from aberrant activation of the immune system are termed autoimmune diseases.
Immunology Research Products Areas
Products for Immunology Research - Page 9
- Cat.No. Product Name Information/Activity
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BCC1256
Leflunomide
Leflunomide is a pyrimidine synthesis inhibitor, inhibiting dihydroorotate dehydrogenase, and acts as a disease-modifying antirheumatic drug.
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BCC1186
Mercaptopurine (6-MP)
6-Mercaptopurine is a purine analogue which acts as an antagonist of the endogenous purines and has been widely used as antileukemic agent and immunosuppressive drug.
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BCC7382
MNITMT
177653-76-8
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BCC2290
Mycophenolate Mofetil
Mycophenolate Mofetil is an immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50s of 39 nM and 27 nM, respectively.
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BCC3592
Rapamycin (Sirolimus)
Rapamycin (Sirolimus) is a potent and specific mTOR inhibitor with an IC50 of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant.
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BCC1975
Tacalcitol
Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium.
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BCC7320
Tautomycetin
119757-73-2
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BCC4734
4-Hydroxy-Teriflunomide
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BCC2220
Thioguanine
6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.
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BCN5984
Triptolide
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory and antiproliferative effects. Triptolide is a NF-κB activation inhibitor.
