Endocrinology Research

Endocrinology is the study of hormones, their signaling pathways, and the diseases associated with them. The endocrine system is one of two mechanisms in the human body that is responsible for regulating and integrating the function of cells, the other being the nervous system.

Endocrinology Research Products Areas

Others (280)

Products for Endocrinology Research - Page 22

Cat.No. Product Name Information/Activity
BCC5968 [D-p-Cl-Phe6,Leu17]-VIP 102805-45-8
BCC7929 DLPC Selective liver receptor homolog-1 (LRH-1) agonist
BCC1957 Sobetirome Sobetirome is a thyroid hormone receptor β (TRβ)-specific agonist which bind selectively to TRβ-1 with an EC50 of 0.16 μM.
BCC6026 SID 7969543 868224-64-0
BCN3793 Guggulsterone Z Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt. Guggulsterone, a farnesoid X receptor (FXR) antagonist, decreases CDCA-induced FXR activation with IC50s of 17 and 15 μM for Z- and E-Guggulsterone, respectively.
BCC7712 Z-Guggulsterone Z-guggulsterone, a constituent of Indian Ayurvedic medicinal plant Commiphora mukul, inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.
BCN1419 3,3'',5-Triiodo-L-thyronine Sodium Salt Liothyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.
BCC5014 Azilsartan Azilsartan(TAK-536) is a specific and potent angiotensin II type 1 receptor antagonist with IC50 of 2.6 nM.
BCC2560 Irbesartan Irbesartan is a highly potent and specific angiotensin II type 1 (AT1) receptor antagonist with IC50 of 1.3 nM.