Phosphodiesterase
Phosphodiesterases (PDEs) are a family of phosphohydrolyases that catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). PDEs regulate the second messengers by controlling their degradation.
Products for Phosphodiesterase - Page 2
- Cat.No. Product Name Information/Activity
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BCC7502
IBMX
IBMX is a broad-spectrum phosphodiesterase (PDE) inhibitor, with IC50s of 6.5, 26.3 and 31.7 μM for PDE3, PDE4 and PDE5, respectively.
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BCC7188
ICI 63197
27277-00-5
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BCC7066
MDL 12330A hydrochloride
Cyclic nucleotide PDE inhibitor; also adenylyl cyclase inhibitor
-
BCC7549
Mesopram
189940-24-7
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BCC4374
Milrinone
Milrinone is a PDE3 inhibitor, and also an inotrope and vasodilator.
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BCC6692
MMPX
78033-08-6
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BCC6645
MY-5445
MY-5445 is a specific phosphodiesterase type 5 (PDE5) inhibitor. MY-5445 selectively inhibits cGMP PDE with a Ki of 1.3 μM.
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BCC6215
Piclamilast
144035-83-6
-
BCC6638
Ro 20-1724
29925-17-5
-
BCC2282
Rolipram
Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC50s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
