Cancer Immunology

Cancer Immunology refers to the relationship between immune function and cancer. The immunological mechanisms involved in cancer growth are highly complex and provide numerous potential points for intervention with small molecules, including extracellular enzymes, receptors and intracellular signal transduction pathways.

Cancer Immunology Products Targets

Products for Cancer Immunology - Page 17

Cat.No. Product Name Information/Activity
BCC6158 680C91 163239-22-3
BCC2556 Febuxostat Febuxostat(TEI 6720;TMX 67 ) is selective xanthine oxidase inhibitor with Ki of 0.6 nM.
BCC1647 INCB024360 analogue IDO5L is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 67 nM.
BCC6060 MDL 72527 93565-01-6
BCC5584 Indoximod (NLG-8189) Indoximod (D-1MT, NLG8189) is an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor with a Ki of 19 μM.
BCC7791 Tranylcypromine hydrochloride Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
BCC6173 Carbazeran citrate 153473-94-0
BCC7413 ZK 756326 874911-96-3
BCC7572 BMS CCR2 22 BMS CCR2 22 is a potent, specific and high affinity CC-type chemokine receptor 2 (CCR2) antagonist with excellent binding affinity (binding IC50 of 5.1 nM) and potent functional antagonism (calcium flux IC50 of 18 nM and chemotaxis IC50 of 1 nM).
BCC6029 BX 471 BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a Ki of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.