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Psoracorylifol B

CAS# 879290-98-9

Psoracorylifol B

Catalog No. BCN7884----Order now to get a substantial discount!

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Chemical structure

Psoracorylifol B

3D structure

Chemical Properties of Psoracorylifol B

Cas No. 879290-98-9 SDF Download SDF
PubChem ID 101401747 Appearance Powder
Formula C18H24O3 M.Wt 288.38
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 4-[(1R,2S,5R,7R)-2-ethenyl-2-methyl-5-propan-2-yl-6,8-dioxabicyclo[3.2.1]octan-7-yl]phenol
SMILES CC(C)C12CCC(C(O1)C(O2)C3=CC=C(C=C3)O)(C)C=C
Standard InChIKey BPUKUJAZQKFJAN-XDNAFOTISA-N
Standard InChI InChI=1S/C18H24O3/c1-5-17(4)10-11-18(12(2)3)20-15(16(17)21-18)13-6-8-14(19)9-7-13/h5-9,12,15-16,19H,1,10-11H2,2-4H3/t15-,16+,17-,18+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Psoracorylifol B

The herbs of Psoralea corylifolia Linn

Biological Activity of Psoracorylifol B

Description1. Psoracorylifol B has antimicrobial activity.
TargetsAntifection

Psoracorylifol B Dilution Calculator

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Psoracorylifol B Molarity Calculator

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Preparing Stock Solutions of Psoracorylifol B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4676 mL 17.3382 mL 34.6765 mL 69.3529 mL 86.6912 mL
5 mM 0.6935 mL 3.4676 mL 6.9353 mL 13.8706 mL 17.3382 mL
10 mM 0.3468 mL 1.7338 mL 3.4676 mL 6.9353 mL 8.6691 mL
50 mM 0.0694 mL 0.3468 mL 0.6935 mL 1.3871 mL 1.7338 mL
100 mM 0.0347 mL 0.1734 mL 0.3468 mL 0.6935 mL 0.8669 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Psoracorylifol B

Scalable asymmetric total syntheses of (+)-Psoracorylifol B and (+)-ent-Psoracorylifol C.[Pubmed:24819702]

Org Lett. 2014 Jun 6;16(11):2986-9.

The first, asymmetric total syntheses of potent antimicrobial Psoracorylifol B (>1.3 g obtained, dr 10.5:1) with a 9.4% overall yield on a gram scale in 14 steps and ent-Psoracorylifol C with a 4.3% yield in 16 steps were achieved. The key features of our synthesis include (i) sequential, rarely explored Achmatowicz rearrangement/bicycloketalization to construct the 6,8-dioxabicyclo[3.2.1]octane core, and (ii) Cu-mediated SN2' methylation or Johnson-Claisen rearrangement to stereoselectively install the all-carbon quaternary stereocenter. This concise, highly efficient, and scalable synthetic route may provide expedited and practical access to psoracorylifols and their analogues for further biological activity evaluation.

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