Prionoid B

CAS# 879324-75-1

Prionoid B

Catalog No. BCN3217----Order now to get a substantial discount!

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Prionoid B:5mg Please Inquire In Stock
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Prionoid B:20mg Please Inquire In Stock
Prionoid B:50mg Please Inquire In Stock

Quality Control of Prionoid B

Number of papers citing our products

Chemical structure

Prionoid B

3D structure

Chemical Properties of Prionoid B

Cas No. 879324-75-1 SDF Download SDF
PubChem ID 102004771 Appearance Powder
Formula C20H22O3 M.Wt 310.4
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1=C2C(=O)C(OC3=C2C(=CC(=C3O)C(C)C)C=C1)C=C(C)C
Standard InChIKey WLCQIECMEDJZSS-UHFFFAOYSA-N
Standard InChI InChI=1S/C20H22O3/c1-10(2)8-15-19(22)16-12(5)6-7-13-9-14(11(3)4)18(21)20(23-15)17(13)16/h6-9,11,15,21H,1-5H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Prionoid B

The roots of Salvia prionitis

Biological Activity of Prionoid B

DescriptionPrionoid B is a natural product from Salvia prionitis.

Protocol of Prionoid B

Structure Identification
Planta Med. 2005 Sep;71(9):861-6.

Novel cytotoxic seco-abietane rearranged diterpenoids from Salvia prionitis.[Pubmed: 16206042 ]


METHODS AND RESULTS:
Six novel 4,5-seco-rearranged abietane diterpenoids, including one tetracyclic diterpenoid, prionoid A (1), two tricyclic diterpenoids, Prionoid B (2) and prionoid C (3), and three dicyclic diterpenoids, prionoid D (4), prionoid E (5), and prionoid F (6), were isolated from the roots of Salvia prionitis Hance (Labiatae). Their structures were elucidated using spectroscopic analysis.
CONCLUSIONS:
The structure of 1 was further confirmed by a single-crystal X-ray diffraction determination. Moreover, it was found that 4 (IC50 = 0.41 microM) and 5 (IC50 = 0.72 microM) showed significant cytotoxic activity against P-388 and A-549 cell lines, respectively.

Prionoid B Dilution Calculator

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Prionoid B Molarity Calculator

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Preparing Stock Solutions of Prionoid B

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2216 mL 16.1082 mL 32.2165 mL 64.433 mL 80.5412 mL
5 mM 0.6443 mL 3.2216 mL 6.4433 mL 12.8866 mL 16.1082 mL
10 mM 0.3222 mL 1.6108 mL 3.2216 mL 6.4433 mL 8.0541 mL
50 mM 0.0644 mL 0.3222 mL 0.6443 mL 1.2887 mL 1.6108 mL
100 mM 0.0322 mL 0.1611 mL 0.3222 mL 0.6443 mL 0.8054 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Prionoid B

Novel cytotoxic seco-abietane rearranged diterpenoids from Salvia prionitis.[Pubmed:16206042]

Planta Med. 2005 Sep;71(9):861-6.

Six novel 4,5-seco-rearranged abietane diterpenoids, including one tetracyclic diterpenoid, prionoid A (1), two tricyclic diterpenoids, prionoids B (2) and C (3), and three dicyclic diterpenoids, prionoids D (4), E (5), and F (6), were isolated from the roots of Salvia prionitis Hance (Labiatae). Their structures were elucidated using spectroscopic analysis. The structure of 1 was further confirmed by a single-crystal X-ray diffraction determination. Moreover, it was found that 4 (IC50 = 0.41 microM) and 5 (IC50 = 0.72 microM) showed significant cytotoxic activity against P-388 and A-549 cell lines, respectively.

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