Peanut procyanidin DCAS# 114637-81-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 114637-81-9 | SDF | Download SDF |
| PubChem ID | 10350652 | Appearance | Powder |
| Formula | C45H36O18 | M.Wt | 864.8 |
| Type of Compound | Procyanidins | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (1R,5R,6S,13R,21R)-5,13-bis(3,4-dihydroxyphenyl)-16-[(2R,3R,4R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-4-yl]-4,12,14-trioxapentacyclo[11.7.1.02,11.03,8.015,20]henicosa-2(11),3(8),9,15,17,19-hexaene-6,9,17,19,21-pentol | ||
| SMILES | C1C(C(OC2=C1C(=CC3=C2C4C(C(O3)(OC5=C(C(=CC(=C45)O)O)C6C(C(OC7=CC(=CC(=C67)O)O)C8=CC(=C(C=C8)O)O)O)C9=CC(=C(C=C9)O)O)O)O)C1=CC(=C(C=C1)O)O)O | ||
| Standard InChIKey | SRWJAXVAWDYXPA-ACNGEOCHSA-N | ||
| Standard InChI | InChI=1S/C45H36O18/c46-18-10-27(54)33-31(11-18)60-41(16-2-5-21(48)25(52)8-16)39(58)37(33)34-28(55)13-29(56)35-38-36-32(62-45(44(38)59,63-43(34)35)17-3-6-22(49)26(53)9-17)14-23(50)19-12-30(57)40(61-42(19)36)15-1-4-20(47)24(51)7-15/h1-11,13-14,30,37-41,44,46-59H,12H2/t30-,37+,38+,39+,40+,41+,44+,45+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Peanut procyanidin D Dilution Calculator
Peanut procyanidin D Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.1563 mL | 5.7817 mL | 11.5634 mL | 23.1267 mL | 28.9084 mL |
| 5 mM | 0.2313 mL | 1.1563 mL | 2.3127 mL | 4.6253 mL | 5.7817 mL |
| 10 mM | 0.1156 mL | 0.5782 mL | 1.1563 mL | 2.3127 mL | 2.8908 mL |
| 50 mM | 0.0231 mL | 0.1156 mL | 0.2313 mL | 0.4625 mL | 0.5782 mL |
| 100 mM | 0.0116 mL | 0.0578 mL | 0.1156 mL | 0.2313 mL | 0.2891 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Peanut procyanidin C
Catalog No.:BCN0902
CAS No.:2095621-31-9
- Peanut procyanidin B
Catalog No.:BCN0901
CAS No.:2085301-50-2
- Peanut procyanidin A
Catalog No.:BCN0900
CAS No.:1802175-67-2
- Cinnamtannin B1
Catalog No.:BCN0899
CAS No.:88082-60-4
- Procyanidin C2
Catalog No.:BCN0898
CAS No.:37064-31-6
- Procyanidin B8
Catalog No.:BCN0897
CAS No.:12798-60-6
- Procyanidin B7
Catalog No.:BCN0896
CAS No.:12798-59-3
- Procyanidin B6
Catalog No.:BCN0895
CAS No.:12798-58-2
- Procyanidin A7
Catalog No.:BCN0894
CAS No.:114569-32-3
- Procyanidin A6
Catalog No.:BCN0893
CAS No.:114569-31-2
- Procyanidin A5
Catalog No.:BCN0892
CAS No.:111466-30-9
- Cinnamtannin A3
Catalog No.:BCN0891
CAS No.:86631-39-2
- Peanut procyanidin E
Catalog No.:BCN0904
CAS No.:2095621-10-4
- Peanut procyanidin F
Catalog No.:BCN0905
CAS No.:2095621-25-1
- Leucocyanidin
Catalog No.:BCN0906
CAS No.:69256-15-1
- Procyanidin B1 3-O-gallate
Catalog No.:BCN0907
CAS No.:79907-45-2
- Procyanidin B2 3-O-gallate
Catalog No.:BCN0908
CAS No.:109280-47-9
- Procyanidin B4 3'-O-gallate
Catalog No.:BCN0909
CAS No.:89064-33-5
- 2-O-Acetylzeylenone
Catalog No.:BCN0910
CAS No.:358748-29-5
- Cinnamtannin A4
Catalog No.:BCN0911
CAS No.:88847-05-6
- Oenothein B
Catalog No.:BCN0912
CAS No.:104987-36-2
- Cinnamtannin B2
Catalog No.:BCN0913
CAS No.:88038-12-4
- Cinnamtannin D1
Catalog No.:BCN0914
CAS No.:97233-06-2
- Cinnamtannin D2
Catalog No.:BCN0915
CAS No.:97233-47-1
Trimeric and Tetrameric A-Type Procyanidins from Peanut Skins.[Pubmed:28231711]
J Nat Prod. 2017 Feb 24;80(2):415-426.
Peanut skins are a rich source of oligomeric and polymeric procyanidins. The oligomeric fractions are dominated by dimers, trimers, and tetramers. A multistep chromatographic fractionation led to the isolation of four new A-type procyanidins of tri- and tetrameric structures. The structures of the new trimers were defined by NMR, electronic circular dichroism, and MS data as epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->8,2beta-->O-->7)-catec hin, peanut procyanidin B (3), and epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->6)-catechin, peanut procyanidin C (4). The new tetramers were defined as epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->6)-epicatechin-(4beta- ->8,2beta-->O-->7)-catechin, peanut procyanidin E (1), and epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin-(4beta-->6)-epicatechin-(4beta- ->8,2beta-->O-->7)-epicatechin, peanut procyanidin F (2). In addition, both A-type dimers A1, epicatechin-(4beta-->8,2beta-->O-->7)-catechin, and A2, epicatechin-(4beta-->8,2beta-->O-->7)-epicatechin, as well as two known peanut trimers, ent-epicatechin-(4beta-->6)-epicatechin-(4beta-->8,2beta-->O-->7)-catechin, peanut procyanidin A (5), and epicatechin-(4beta-->8)-epicatechin-(4beta-->8,2beta-->O-->7)-catechin, Peanut procyanidin D (6), were also isolated. Dimer A1, the four trimers, and two tetramers were evaluated for anti-inflammatory activity in an in vitro assay, in which LPS-stimulated macrophages were responding with secretion of TNF-alpha, a pro-inflammatory cytokine. Tetramer F (2) was the most potent, suppressing TNF-alpha secretion to 82% at 8.7 muM (10 mug/mL), while tetramer E (1) at the same concentrations caused a 4% suppression. The results of the TNF-alpha secretion inhibition indicate that small structural differences, as in peanut procyanidin tetramers E and F, can be strongly differentiated in biological systems.
