Pancixanthone ACAS# 174232-30-5 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 174232-30-5 | SDF | Download SDF |
| PubChem ID | 10852567 | Appearance | Powder |
| Formula | C18H16O5 | M.Wt | 312.32 |
| Type of Compound | Xanthones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1,3,5-trihydroxy-4-(2-methylbut-3-en-2-yl)xanthen-9-one | ||
| SMILES | CC(C)(C=C)C1=C(C=C(C2=C1OC3=C(C2=O)C=CC=C3O)O)O | ||
| Standard InChIKey | PNPYKPQUXNWIPR-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C18H16O5/c1-4-18(2,3)14-12(21)8-11(20)13-15(22)9-6-5-7-10(19)16(9)23-17(13)14/h4-8,19-21H,1H2,2-3H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Pancixanthone A shows a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L. infantum and against the amastigote forms of L. infantum. 2. Pancixanthone A may have antimalarial activity. |
| Targets | Antifection |
Pancixanthone A Dilution Calculator
Pancixanthone A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.2018 mL | 16.0092 mL | 32.0184 mL | 64.0369 mL | 80.0461 mL |
| 5 mM | 0.6404 mL | 3.2018 mL | 6.4037 mL | 12.8074 mL | 16.0092 mL |
| 10 mM | 0.3202 mL | 1.6009 mL | 3.2018 mL | 6.4037 mL | 8.0046 mL |
| 50 mM | 0.064 mL | 0.3202 mL | 0.6404 mL | 1.2807 mL | 1.6009 mL |
| 100 mM | 0.032 mL | 0.1601 mL | 0.3202 mL | 0.6404 mL | 0.8005 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Methyl 3-(2,4-dihydroxyphenyl)propionate
Catalog No.:BCN1525
CAS No.:17422-90-1
- 3-Chloro-4-hydroxypiperidin-2-one
Catalog No.:BCN3992
CAS No.:174204-83-2
- Aristolochic acid D
Catalog No.:BCN2902
CAS No.:17413-38-6
- 3-(4-Pyridyl)-D-Alanine.2HCl
Catalog No.:BCC2650
CAS No.:174096-41-4
- Tomatine
Catalog No.:BCN2966
CAS No.:17406-45-0
- Bevirimat
Catalog No.:BCC5312
CAS No.:174022-42-5
- Dehydroabietic acid
Catalog No.:BCN1119
CAS No.:1740-19-8
- Nepicastat
Catalog No.:BCC1795
CAS No.:173997-05-2
- 5-Acetyl-6-hydroxy-2-(1-hydroxy-1-methylethyl)benzofuran
Catalog No.:BCN7495
CAS No.:173992-05-7
- 22-Hydroxy-3-oxo-12-ursen-30-oic acid
Catalog No.:BCN1526
CAS No.:173991-81-6
- Tanshinone IIB
Catalog No.:BCN1118
CAS No.:17397-93-2
- SYM 2206
Catalog No.:BCC6866
CAS No.:173952-44-8
- Apigenin 7-O-(2G-rhamnosyl)gentiobioside
Catalog No.:BCN1524
CAS No.:174284-20-9
- Epimedin K
Catalog No.:BCN8201
CAS No.:174286-13-6
- Caohuoside E
Catalog No.:BCN8198
CAS No.:174286-23-8
- Astragaloside
Catalog No.:BCN5959
CAS No.:17429-69-5
- Picropodophyllotoxin
Catalog No.:BCN2585
CAS No.:17434-18-3
- Tsugaric acid A
Catalog No.:BCN2980
CAS No.:174391-64-1
- Riluzole
Catalog No.:BCC3849
CAS No.:1744-22-5
- Amiloride HCl dihydrate
Catalog No.:BCC5068
CAS No.:17440-83-4
- Sanggenol A
Catalog No.:BCN3602
CAS No.:174423-30-4
- Tipranavir
Catalog No.:BCC2002
CAS No.:174484-41-4
- alpha-Spinasterol glucoside
Catalog No.:BCN1120
CAS No.:1745-36-4
- 2-Allylphenol
Catalog No.:BCC8518
CAS No.:1745-81-9
Antileishmanial polyphenols from Garcinia vieillardii.[Pubmed:17826924]
Fitoterapia. 2008 Jan;79(1):42-6.
Seven xanthones, the new vieillardiixanthones B and C (1) and (7), pancixanthones A (2), B (3), 1,6-dihydroxyxanthone (6), pyranojacareubin and 5,6-O-dimethyl-2-deprenylrheediaxanthone together with two benzophenones, clusiachromene (4) and 3-geranyl-2,4,6-trihydroxybenzophenone (5) were isolated from the stem bark of the neocaledonian Garcinia vieillardii. 2, 5 and 6 showed a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L. infantum and against the amastigote forms of L. infantum.
Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii.[Pubmed:15474559]
Life Sci. 2004 Nov 5;75(25):3077-85.
The antimalarial activity of 22 xanthones against chloroquino-resistant strains of Plasmodium falciparum was evaluated. Natural caloxanthone C (1), demethylcalabaxanthone (2), calothwaitesixanthone (3), calozeyloxanthone (4), dombakinaxanthone (5), macluraxanthone (6), and 6-deoxy-gamma-mangostin (7) were isolated from Calophyllum caledonicum. 1,6-dihydroxyxanthone (8), Pancixanthone A (9), isocudraniaxanthone B (10), isocudraniaxanthone A (11), 2-deprenylrheediaxanthone B (12) and 1,4,5-trihydroxyxanthone (13) were isolated from Garcinia vieillardii. Moreover, synthetic compounds (14-22) are analogues or intermediates of xanthones purified from Calophyllum caledonicum (Oger J.M., Morel C., Helesbeux J.J., Litaudon M., Seraphin D., Dartiguelongue C., Larcher G., Richomme P., Duval O. 2003. First 2-Hydroxy-3-Methylbut-3-Enyl substituted xanthones isolated from Plants: structure elucidation, synthesis and antifungal activity. Natural Product Research 17(3), 195-199; Helesbeux J.J., Duval O., Dartiguelongue C., Seraphin D., Oger J.M., Richomme P., 2004. Synthesis of 2-hydroxy-3-methylbut-3-enyl substituted coumarins and xanthones as natural products. Application of the Schenck ene reaction of singlet oxygen with ortho-prenylphenol precursors. Tetrahedron 60(10), 2293-2300). The relationship between antimalarial activity and molecular structure of xanthones has also been explored. The most potent xanthones (2), (3) and (7) (IC50 = c.a. 1.0 microg/mL) are 1,3,7 trioxygenated and prenylated on the positions 2 and 8.
[Xanthones from leaves of Calophyllum inophyllum Linn].[Pubmed:19408685]
Yao Xue Xue Bao. 2009 Feb;44(2):154-7.
To study the xanthones from the leaves of Calophyllum inophyllum Linn., several chromatography methods were employed to isolate the constituents. Investigation on the CHCl3 extract led to the isolation of a new xanthone named inophyxanthone A (1) and four known compounds, which were Pancixanthone A (2), gerontoxanthone B (3), jacareubin (4) and pyranojacareubin (5). Among them, compound 2 was obtained from this plant firstly, and compound 3 was obtained for the first time from this genus. The structure of inophyxanthone A (1) was identified as 1, 3, 5-trihydroxy-2-(1, 1-dimethylallyl)xanthone by spectral analysis.
