Amiloride HCl dihydrateCAS# 17440-83-4 |
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Chemical structure
3D structure
| Cas No. | 17440-83-4 | SDF | Download SDF |
| PubChem ID | 68540 | Appearance | Powder |
| Formula | C6H13Cl2N7O3 | M.Wt | 302.12 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : 100 mg/mL (330.99 mM; Need ultrasonic and warming) H2O : 2 mg/mL (6.62 mM; Need ultrasonic) | ||
| Chemical Name | 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide;dihydrate;hydrochloride | ||
| SMILES | C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N.O.O.Cl | ||
| Standard InChIKey | LTKVFMLMEYCWMK-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Amiloride HCl dihydrate Dilution Calculator
Amiloride HCl dihydrate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.3099 mL | 16.5497 mL | 33.0994 mL | 66.1989 mL | 82.7486 mL |
| 5 mM | 0.662 mL | 3.3099 mL | 6.6199 mL | 13.2398 mL | 16.5497 mL |
| 10 mM | 0.331 mL | 1.655 mL | 3.3099 mL | 6.6199 mL | 8.2749 mL |
| 50 mM | 0.0662 mL | 0.331 mL | 0.662 mL | 1.324 mL | 1.655 mL |
| 100 mM | 0.0331 mL | 0.1655 mL | 0.331 mL | 0.662 mL | 0.8275 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Amiloride HCl dihydrate is a potent epithelial sodium channel blocker.
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Amiloride hydrochloride dihydrate (MK-870 hydrochloride dihydrate) is an inhibitor of both epithelial sodium channel (ENaC) and urokinase-type plasminogen activator receptor (uTPA). Amiloride hydrochloride dihydrate is a blocker of polycystin-2 (PC2; TRPP2) channel.
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