Nirtetralin

CAS# 78185-63-4

Nirtetralin

Catalog No. BCN3755----Order now to get a substantial discount!

Product Name & Size Price Stock
Nirtetralin:5mg Please Inquire In Stock
Nirtetralin:10mg Please Inquire In Stock
Nirtetralin:20mg Please Inquire In Stock
Nirtetralin:50mg Please Inquire In Stock

Quality Control of Nirtetralin

Number of papers citing our products

Chemical structure

Nirtetralin

3D structure

Chemical Properties of Nirtetralin

Cas No. 78185-63-4 SDF Download SDF
PubChem ID 182644 Appearance Cryst.
Formula C24H30O7 M.Wt 430.5
Type of Compound Lignans Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (5R,6S,7S)-5-(3,4-dimethoxyphenyl)-4-methoxy-6,7-bis(methoxymethyl)-5,6,7,8-tetrahydrobenzo[f][1,3]benzodioxole
SMILES COCC1CC2=CC3=C(C(=C2C(C1COC)C4=CC(=C(C=C4)OC)OC)OC)OCO3
Standard InChIKey LHQDZANQXMRHIV-LZJOCLMNSA-N
Standard InChI InChI=1S/C24H30O7/c1-25-11-16-8-15-10-20-23(31-13-30-20)24(29-5)22(15)21(17(16)12-26-2)14-6-7-18(27-3)19(9-14)28-4/h6-7,9-10,16-17,21H,8,11-13H2,1-5H3/t16-,17-,21+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Nirtetralin

The herbs of Phyllanthus niruri Linn.

Biological Activity of Nirtetralin

Description1. Nirtetralin suppresses effectively both HBsAg and HBeAg expression.
TargetsHBV

Nirtetralin Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Nirtetralin Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Nirtetralin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3229 mL 11.6144 mL 23.2288 mL 46.4576 mL 58.072 mL
5 mM 0.4646 mL 2.3229 mL 4.6458 mL 9.2915 mL 11.6144 mL
10 mM 0.2323 mL 1.1614 mL 2.3229 mL 4.6458 mL 5.8072 mL
50 mM 0.0465 mL 0.2323 mL 0.4646 mL 0.9292 mL 1.1614 mL
100 mM 0.0232 mL 0.1161 mL 0.2323 mL 0.4646 mL 0.5807 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Nirtetralin

Lignans with anti-hepatitis B virus activities from Phyllanthus niruri L.[Pubmed:22131154]

Phytother Res. 2012 Jul;26(7):964-8.

One new lignan, Nirtetralin B, along with its two known stereoisomers were isolated from Phyllanthus niruri L. The structure of the new compound was determined by spectroscopy experiments and x-ray diffraction analysis. These lignans were assayed for anti-hepatitis B virus activities in vitro. Nirtetralin and Nirtetralin A, B effectively suppressed the secretion of the HBV antigens in a dose-dependent manner with IC(5)(0) values for HBsAg of 9.5 microM (Nirtetralin A), 16.7 microM (Nirtetralin B) and 97.2 microM (Nirtetralin), IC(5)(0) values for HBeAg of 17.4 microM (Nirtetralin A), 69.3 microM (Nirtetralin B) and 232.0 microM (Nirtetralin), respectively.

Screening of 25 compounds isolated from Phyllanthus species for anti-human hepatitis B virus in vitro.[Pubmed:12748977]

Phytother Res. 2003 May;17(5):449-53.

Using an HBV-producing cell line and inhibition of the expression of the HBsAg and HBeAg as antiviral indicators, a study was conducted on 25 compounds isolated from four Phyllanthus (Euphorbiaceae) plants, including P. amarus Schum. & Thonn., P. multi florus Willd., P. tenellus Roxb. and P. virgatus Forst. f. It was found that niranthin (1), Nirtetralin (3), hinokinin (5) and geraniin (13) at the non-cytotoxic concentration of 50 micro m, suppressed effectively both HBsAg and HBeAg expression, with the highest inhibition at 74.3%, 45.3%; 69.6%, 33.9%; 68.1%, 52.3%; 32.1%, 46.6%, respectively. Of these, niranthin (1) showed the best anti-HBsAg activity, while the most potent anti-HBeAg activity was observed with hinokinin (5).

Keywords:

Nirtetralin,78185-63-4,Natural Products, buy Nirtetralin , Nirtetralin supplier , purchase Nirtetralin , Nirtetralin cost , Nirtetralin manufacturer , order Nirtetralin , high purity Nirtetralin

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: