Home >> Research Area >>Natural Products>>Flavonoids>> Neocyclomorusin

Neocyclomorusin

CAS# 62596-35-4

Neocyclomorusin

Catalog No. BCN3601----Order now to get a substantial discount!

Product Name & Size Price Stock
Neocyclomorusin:5mg Please Inquire In Stock
Neocyclomorusin:10mg Please Inquire In Stock
Neocyclomorusin:20mg Please Inquire In Stock
Neocyclomorusin:50mg Please Inquire In Stock

Quality Control of Neocyclomorusin

Number of papers citing our products

Chemical structure

Neocyclomorusin

3D structure

Chemical Properties of Neocyclomorusin

Cas No. 62596-35-4 SDF Download SDF
PubChem ID 5481973 Appearance Yellow powder
Formula C25H24O7 M.Wt 436.5
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC1(C=CC2=C3C(=C(C=C2O1)O)C(=O)C4=C(O3)C5=C(C=C(C=C5)O)OC(C4)C(C)(C)O)C
Standard InChIKey BKIVBOLDWRIFMA-UHFFFAOYSA-N
Standard InChI InChI=1S/C25H24O7/c1-24(2)8-7-14-18(32-24)11-16(27)20-21(28)15-10-19(25(3,4)29)30-17-9-12(26)5-6-13(17)22(15)31-23(14)20/h5-9,11,19,26-27,29H,10H2,1-4H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Neocyclomorusin

The root bark of Morus alba L.

Biological Activity of Neocyclomorusin

Description1. Neocyclomorusin displays minimal inhibitory concentration (MIC) value of 4 ug/mL against Klebsiella pneumoniae ATCC11296, Enterobacter cloacae BM47.
TargetsAntifection

Neocyclomorusin Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Neocyclomorusin Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Neocyclomorusin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.291 mL 11.4548 mL 22.9095 mL 45.819 mL 57.2738 mL
5 mM 0.4582 mL 2.291 mL 4.5819 mL 9.1638 mL 11.4548 mL
10 mM 0.2291 mL 1.1455 mL 2.291 mL 4.5819 mL 5.7274 mL
50 mM 0.0458 mL 0.2291 mL 0.4582 mL 0.9164 mL 1.1455 mL
100 mM 0.0229 mL 0.1145 mL 0.2291 mL 0.4582 mL 0.5727 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Neocyclomorusin

[Chemical constituents from Morus notabilis and their cytotoxic effect].[Pubmed:26234140]

Yao Xue Xue Bao. 2015 May;50(5):579-82.

Une new flavonoids named as notabilisin K (1), together with four known compounds, morusin (2), mulberrofuran A (3), Neocyclomorusin (4) and mornigrol F (5) are separated from 95% ethanol extracts of the twigs of Morus notabilis. Compounds 2-5 are separated from this plant for the first time. Notabilisin I, notabilisin J exhibits certain effect against cells of HCT-116, HepG2 and A2780 with IC50 values ranging from 1.47 mumol x L(-1) to 5.46 mumol x L(-1). Morusin exhibits strong effect against five kinds of human cancer cells (BGC823, A2780, HCT-116, HepG2 and NCI-H1650) with IC50 values ranging from 0.74 mumol x L(-1) to 1.58 mumol x L(-1).

Antibacterial activity of nineteen selected natural products against multi-drug resistant Gram-negative phenotypes.[Pubmed:26753111]

Springerplus. 2015 Dec 30;4:823.

The present study was designed to assess the antimicrobial activity of 19 natural products belonging to terpenoids, alkaloids, thiophenes and phenolics against a panel of 14 Gram-negative multidrug-resistant (MDR) bacteria. The results demonstrated that amongst the studied compounds, alkaloids and terpenoids were less active contrary to flavonoids: Neocyclomorusin (3) and candidone (6) and isoflavonoids: neobavaisoflavone (8) and daidzein (12). Thiophene, 2-(penta-1,3-diynyl)-5-(3,4-dihydroxybut-1-ynyl)thiophene (17) showed moderate and selective activities. Compounds 3, 6, 8 and 12 displayed minimal inhibitory concentration (MIC) ranged from 4 to 256 mug/mL on all the 14 tested bacteria. MIC values below 10 mug/mL were obtained with 8, 3, 6 and 12 against 50, 42.9, 35.7 and 21.4 % of the tested bacteria. The lowest MIC value of 4 mug/mL was obtained with compound 3 against Klebsiella pneumoniae ATCC11296, Enterobacter cloacae BM47, compound 6 against Escherichia coli ATCC8739, K. pneumoniae ATCC11296, E. cloacae BM47 and compound 8 against K. pneumoniae ATCC11296 and E. cloacae BM47. The activity of flavonoid 3 was better or equal to that of chloramphenicol in all tested K. pneumoniae, Providencia stuartii, E. aerogenes, E. cloacae and Pseudomonas aeruginosa strains. Within isoflavonoids, neobavaisoflavone scaffold was detected as a pharmacophoric moiety. This study indicates that natural products such as 3, 6 and 8 could be explored more to develop antimicrobial drugs to fight MDR bacterial infections.

Keywords:

Neocyclomorusin,62596-35-4,Natural Products, buy Neocyclomorusin , Neocyclomorusin supplier , purchase Neocyclomorusin , Neocyclomorusin cost , Neocyclomorusin manufacturer , order Neocyclomorusin , high purity Neocyclomorusin

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: