Murrayanol

CAS# 144525-81-5

Murrayanol

Catalog No. BCN3178----Order now to get a substantial discount!

Product Name & Size Price Stock
Murrayanol:5mg Please Inquire In Stock
Murrayanol:10mg Please Inquire In Stock
Murrayanol:20mg Please Inquire In Stock
Murrayanol:50mg Please Inquire In Stock

Quality Control of Murrayanol

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Chemical structure

Murrayanol

3D structure

Chemical Properties of Murrayanol

Cas No. 144525-81-5 SDF Download SDF
PubChem ID 9975970 Appearance Cryst.
Formula C24H29NO2 M.Wt 363.5
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-[(2E)-3,7-dimethylocta-2,6-dienyl]-7-methoxy-6-methyl-9H-carbazol-2-ol
SMILES CC1=C(C=C2C(=C1)C3=C(N2)C(=C(C=C3)O)CC=C(C)CCC=C(C)C)OC
Standard InChIKey RTEIBQDXHHQYRJ-CXUHLZMHSA-N
Standard InChI InChI=1S/C24H29NO2/c1-15(2)7-6-8-16(3)9-10-19-22(26)12-11-18-20-13-17(4)23(27-5)14-21(20)25-24(18)19/h7,9,11-14,25-26H,6,8,10H2,1-5H3/b16-9+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Murrayanol

The leaves of Murraya koenigii

Biological Activity of Murrayanol

Description1. Murrayanol has antioxidant activity. 2. Murrayanol shows an IC50 of 109 μg/mL against hPGHS-1 and an IC50 of 218 μg/mL against hPGHS-2 in antiinflammatory assays.
TargetsTopoisomerase | Antifection

Murrayanol Dilution Calculator

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Murrayanol Molarity Calculator

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Preparing Stock Solutions of Murrayanol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.751 mL 13.7552 mL 27.5103 mL 55.0206 mL 68.7758 mL
5 mM 0.5502 mL 2.751 mL 5.5021 mL 11.0041 mL 13.7552 mL
10 mM 0.2751 mL 1.3755 mL 2.751 mL 5.5021 mL 6.8776 mL
50 mM 0.055 mL 0.2751 mL 0.5502 mL 1.1004 mL 1.3755 mL
100 mM 0.0275 mL 0.1376 mL 0.2751 mL 0.5502 mL 0.6878 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Murrayanol

Biologically active carbazole alkaloids from Murraya koenigii.[Pubmed:10563914]

J Agric Food Chem. 1999 Feb;47(2):444-7.

The bioassay guided fractionation of the acetone extract of the fresh leaves of Murraya koenigii resulted in the isolation of three bioactive carbazole alkaloids, mahanimbine (1), Murrayanol (2), and mahanine (3), as confirmed from their (1)H and (13)C NMR spectral data. Compound 2 showed an IC(50) of 109 microg/mL against hPGHS-1 and an IC(50) of 218 microg/mL against hPGHS-2 in antiinflammatory assays, while compound 1 displayed antioxidant activity at 33.1 microg/mL. All three compounds were mosquitocidal and antimicrobial and exhibited topoisomerase I and II inhibition activities.

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