(-)-Hydroxycitric acid lactoneCAS# 27750-13-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 27750-13-6 | SDF | Download SDF |
| PubChem ID | 9991606 | Appearance | White powder |
| Formula | C6H6O7 | M.Wt | 190.1 |
| Type of Compound | Miscellaneous | Storage | Desiccate at -20°C |
| Synonyms | Garcinia acid lactone | ||
| Solubility | Freely soluble in methanol and water; insoluble in chloroform and petroleum ether | ||
| Chemical Name | (2S,3S)-3-hydroxy-5-oxooxolane-2,3-dicarboxylic acid | ||
| SMILES | C1C(=O)OC(C1(C(=O)O)O)C(=O)O | ||
| Standard InChIKey | PFHZIWAVXDSFTB-CVYQJGLWSA-N | ||
| Standard InChI | InChI=1S/C6H6O7/c7-2-1-6(12,5(10)11)3(13-2)4(8)9/h3,12H,1H2,(H,8,9)(H,10,11)/t3-,6+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Reference standards. | |||||
(-)-Hydroxycitric acid lactone Dilution Calculator
(-)-Hydroxycitric acid lactone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 5.2604 mL | 26.3019 mL | 52.6039 mL | 105.2078 mL | 131.5097 mL |
| 5 mM | 1.0521 mL | 5.2604 mL | 10.5208 mL | 21.0416 mL | 26.3019 mL |
| 10 mM | 0.526 mL | 2.6302 mL | 5.2604 mL | 10.5208 mL | 13.151 mL |
| 50 mM | 0.1052 mL | 0.526 mL | 1.0521 mL | 2.1042 mL | 2.6302 mL |
| 100 mM | 0.0526 mL | 0.263 mL | 0.526 mL | 1.0521 mL | 1.3151 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Authentication of Garcinia fruits and food supplements using DNA barcoding and NMR spectroscopy.[Pubmed:30002410]
Sci Rep. 2018 Jul 12;8(1):10561.
Garcinia L. (Clusiaceae) fruits are a rich source of (-)-hydroxycitric acid, and this has gained considerable attention as an anti-obesity agent and a popular weight loss food supplement. In this study, we assessed adulteration of morphologically similar samples of Garcinia using DNA barcoding, and used NMR to quantify the content of (-)-hydroxycitric acid and (-)-Hydroxycitric acid lactone in raw herbal drugs and Garcinia food supplements. DNA barcoding revealed that mostly G. gummi-gutta (previously known as G. cambogia) and G. indica were traded in Indian herbal markets, and there was no adulteration. The content of (-)-hydroxycitric acid and (-)-Hydroxycitric acid lactone in the two species varied from 1.7% to 16.3%, and 3.5% to 20.7% respectively. Analysis of ten Garcinia food supplements revealed a large variation in the content of (-)-hydroxycitric acid, from 29 mg (4.6%) to 289 mg (50.6%) content per capsule or tablet. Only one product contained quantifiable amounts of (-)-Hydroxycitric acid lactone. Furthermore the study demonstrates that DNA barcoding and NMR could be effectively used as a regulatory tool to authenticate Garcinia fruit rinds and food supplements.
Organic acids from leaves, fruits, and rinds of Garcinia cowa.[Pubmed:12033807]
J Agric Food Chem. 2002 Jun 5;50(12):3431-4.
Organic acids in fresh leaves, fruits, and dried rinds of Garcinia cowa (G. cowa) were determined by high-performance liquid chromatography. Fresh leaves, fruits, and dried rinds were extracted with water at 120 degrees C for 20-30 min under 15 lbs/in(2) pressure. Also, dried rinds were extracted with solvents (acetone and methanol) using a Soxhlet extractor at 60 degrees C for 8 h each. The samples were injected to HPLC under gradient elution with 0.01 M phosphoric acid and methanol with a flow rate of 0.7 mL/min using UV detection at 210 nm. The major organic acid was found to be (-)-hydroxycitric acid present in leaves, fruits, and rinds to the extent of 1.7, 2.3, and 12.7%, respectively. (-)-Hydroxycitric acid lactone, and oxalic and citric acids are present in leaves, fruits, and rinds in minor quantities. This is the first report on the composition of organic acids from G. cowa.
