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Galangin 3-methyl ether

CAS# 6665-74-3

Galangin 3-methyl ether

Catalog No. BCN3681----Order now to get a substantial discount!

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Chemical structure

Galangin 3-methyl ether

3D structure

Chemical Properties of Galangin 3-methyl ether

Cas No. 6665-74-3 SDF Download SDF
PubChem ID 5281946 Appearance Powder
Formula C16H12O5 M.Wt 284.3
Type of Compound Flavonoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 5,7-dihydroxy-3-methoxy-2-phenylchromen-4-one
SMILES COC1=C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=CC=C3
Standard InChIKey LYISDADPVOHJBJ-UHFFFAOYSA-N
Standard InChI InChI=1S/C16H12O5/c1-20-16-14(19)13-11(18)7-10(17)8-12(13)21-15(16)9-5-3-2-4-6-9/h2-8,17-18H,1H3
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Galangin 3-methyl ether

The rhizomes of Alpinia officinarum Hance

Biological Activity of Galangin 3-methyl ether

Description1. Galangin-3-methylether has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. 2. 3-Methylethergalangin has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase.

Galangin 3-methyl ether Dilution Calculator

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Galangin 3-methyl ether Molarity Calculator

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Preparing Stock Solutions of Galangin 3-methyl ether

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.5174 mL 17.5871 mL 35.1741 mL 70.3482 mL 87.9353 mL
5 mM 0.7035 mL 3.5174 mL 7.0348 mL 14.0696 mL 17.5871 mL
10 mM 0.3517 mL 1.7587 mL 3.5174 mL 7.0348 mL 8.7935 mL
50 mM 0.0703 mL 0.3517 mL 0.7035 mL 1.407 mL 1.7587 mL
100 mM 0.0352 mL 0.1759 mL 0.3517 mL 0.7035 mL 0.8794 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Galangin 3-methyl ether

Bioactivity of flavonoids isolated from Lychnophora markgravii against Leishmania amazonensis amastigotes.[Pubmed:19791501]

Z Naturforsch C. 2009 Jul-Aug;64(7-8):509-12.

The bioactivity of the flavonoids pinostrobin (1), pinocembrin (2), tectochrysin (3), Galangin 3-methyl ether (4), and tiliroside (5) isolated from Lychnophora markgravii aerial parts was investigated in vitro against amastigote stages of Leishmania amazonensis. The compounds were isolated by several chromatographic techniques and their chemical structures were established by ESI-MS and NMR spectroscopic data. The flavonoids 1 and 3 were the most active compounds; they markedly reduced the viability of Leishmania amastigotes.

Trypanocidal activity of Lychnophora staavioides Mart. (Vernonieae, Asteraceae).[Pubmed:13678232]

Phytomedicine. 2003;10(6-7):490-3.

In the continuing search for new compounds with trypanocidal activity for use in blood banks to prevent the transmission of Chagas' disease, a trypanocidal extract of Lychnophora staavioides Mart. (Vernonieae, Asteraceae) was fractionated using several chromatographic techniques and afforded the following flavonoids: tectochrysin, pinostrobin, pinobanksin, pinobanksin 3-acetate, pinocembrin, chrysin, Galangin 3-methyl ether, quercetin 3-methyl ether, chrysoeriol and vicenin-2. The most active compound was quercetin 3-methyl ether, which showed no blood lysis activity and which represents a promising compound for use against T. cruzi in blood banks.

Description

3-O-Methylgalangin (Galangin 3-methyl ether) is a natural flavonoid compound from the rhizome of Alpinia officinarum (AO) with antibacterial activities, which also inhibits pancreatic lipase.

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