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Frangulin A

CAS# 521-62-0

Frangulin A

Catalog No. BCC8174----Order now to get a substantial discount!

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Frangulin A:5mg Please Inquire In Stock
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Quality Control of Frangulin A

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Chemical structure

Frangulin A

3D structure

Chemical Properties of Frangulin A

Cas No. 521-62-0 SDF Download SDF
PubChem ID 196979 Appearance Yellow powder
Formula C21H20O9 M.Wt 416.4
Type of Compound Quinones Storage Desiccate at -20°C
Synonyms Emodin L-rhamnoside; Franguloside; Rhamnoxanthin
Solubility Sparingly soluble in water; slightly soluble in ethanol and methan
Chemical Name 1,8-dihydroxy-3-methyl-6-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyanthracene-9,10-dione
SMILES CC1C(C(C(C(O1)OC2=CC(=C3C(=C2)C(=O)C4=CC(=CC(=C4C3=O)O)C)O)O)O)O
Standard InChIKey DTTVUKLWJFJOHO-FUCRAMRQSA-N
Standard InChI InChI=1S/C21H20O9/c1-7-3-10-14(12(22)4-7)18(26)15-11(17(10)25)5-9(6-13(15)23)30-21-20(28)19(27)16(24)8(2)29-21/h3-6,8,16,19-24,27-28H,1-2H3/t8-,16-,19+,20+,21-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Frangulin A Dilution Calculator

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Frangulin A Molarity Calculator

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Preparing Stock Solutions of Frangulin A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.4015 mL 12.0077 mL 24.0154 mL 48.0307 mL 60.0384 mL
5 mM 0.4803 mL 2.4015 mL 4.8031 mL 9.6061 mL 12.0077 mL
10 mM 0.2402 mL 1.2008 mL 2.4015 mL 4.8031 mL 6.0038 mL
50 mM 0.048 mL 0.2402 mL 0.4803 mL 0.9606 mL 1.2008 mL
100 mM 0.024 mL 0.1201 mL 0.2402 mL 0.4803 mL 0.6004 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Frangulin A

Induction of defence mechanisms in grapevine leaves by emodin- and anthraquinone-rich plant extracts and their conferred resistance to downy mildew.[Pubmed:19447634]

Plant Physiol Biochem. 2009 Sep;47(9):827-37.

The ability of two plant extracts, Rheum palmatum root extract (RPRE) and Frangula alnus bark extract (FABE), to protect Vitis vinifera leaves from Plasmopara viticola infection was evaluated. These natural products are toxic to the pathogen and induce defence reactions in a susceptible cultivar of V. vinifera (V. vinifera cv. Chasselas), including stilbenic phytoalexin accumulation, enhanced peroxidase (EC 1.11.1.7) activity, and a hypersensitive reaction. Inhibition of the first stage of biotrophic hyphal development of P. Viticola by the two plant extracts was observed. HPLC-DAD-MS analysis showed that these two natural extracts contain many phenolic compounds belonging to the anthraquinone family, such as rhein, Frangulin A, emodin, aloe-emodin, chrysophanol, and physcion. Emodin alone is able to impair P. viticola development and to stimulate viniferins and the accumulation of pterostilbene.

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