Ficusin ACAS# 173429-83-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 173429-83-9 | SDF | Download SDF |
| PubChem ID | 15231941 | Appearance | Yellow powder |
| Formula | C25H24O5 | M.Wt | 404.5 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5,7-dihydroxy-3-(4-hydroxyphenyl)-8-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]chromen-4-one | ||
| SMILES | CC1=CC(C(CC1)C(=C)C)C2=C(C=C(C3=C2OC=C(C3=O)C4=CC=C(C=C4)O)O)O | ||
| Standard InChIKey | LRYZMDSDXSWBMU-ZWKOTPCHSA-N | ||
| Standard InChI | InChI=1S/C25H24O5/c1-13(2)17-9-4-14(3)10-18(17)22-20(27)11-21(28)23-24(29)19(12-30-25(22)23)15-5-7-16(26)8-6-15/h5-8,10-12,17-18,26-28H,1,4,9H2,2-3H3/t17-,18+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The seeds of Psoralea corylifolia Linn.
| Description | 1. Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPARγ expression and improve the translocation and activation of GLUT4 in the adipose tissue, suggests that ficusin improves the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitusl. |
| Targets | GLUT | PPAR |
Ficusin A Dilution Calculator
Ficusin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.4722 mL | 12.3609 mL | 24.7219 mL | 49.4438 mL | 61.8047 mL |
| 5 mM | 0.4944 mL | 2.4722 mL | 4.9444 mL | 9.8888 mL | 12.3609 mL |
| 10 mM | 0.2472 mL | 1.2361 mL | 2.4722 mL | 4.9444 mL | 6.1805 mL |
| 50 mM | 0.0494 mL | 0.2472 mL | 0.4944 mL | 0.9889 mL | 1.2361 mL |
| 100 mM | 0.0247 mL | 0.1236 mL | 0.2472 mL | 0.4944 mL | 0.618 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- Rotundanonic acid
Catalog No.:BCN7152
CAS No.:173357-19-2
- Afobazole
Catalog No.:BCC5386
CAS No.:173352-21-1
- Pelargonidin-3,5-O-diglucoside chloride
Catalog No.:BCN1527
CAS No.:17334-58-6
- Aliskiren Hemifumarate
Catalog No.:BCC5018
CAS No.:173334-58-2
- Aliskiren
Catalog No.:BCC1338
CAS No.:173334-57-1
- Isorhamnetin 3-glucoside-7-rhamnoside
Catalog No.:BCN1528
CAS No.:17331-71-4
- Garciniaxanthone E
Catalog No.:BCN1114
CAS No.:173294-74-1
- TC-E 5003
Catalog No.:BCC8008
CAS No.:17328-16-4
- 2,5-Dihydroxy-1-methoxyxanthone
Catalog No.:BCN7577
CAS No.:173220-32-1
- Broussonetine A
Catalog No.:BCN2515
CAS No.:173220-07-0
- Clomipramine HCl
Catalog No.:BCC5036
CAS No.:17321-77-6
- 4-Beta-Hydroxycholesterol
Catalog No.:BCN2752
CAS No.:17320-10-4
New Products
- HMN-214
Catalog No.:BCC2517
CAS No.:173529-46-9
- Naphthoquine phosphate
Catalog No.:BCC1784
CAS No.:173531-58-3
- Compound W
Catalog No.:BCC2341
CAS No.:173550-33-9
- 3,5-Dinitro-Tyr-OH
Catalog No.:BCC3331
CAS No.:17360-11-1
- Oxotremorine sesquifumarate
Catalog No.:BCC6814
CAS No.:17360-35-9
- 2,3-Didehydrosomnifericin
Catalog No.:BCN8005
CAS No.:173614-88-5
- Desoxygambogenin
Catalog No.:BCN3068
CAS No.:173614-93-2
- 3-Galloylquinic acid
Catalog No.:BCN3732
CAS No.:17365-11-6
- TBB
Catalog No.:BCC1988
CAS No.:17374-26-4
- BGC 20-761
Catalog No.:BCC7650
CAS No.:17375-63-2
- Gambogin
Catalog No.:BCN3069
CAS No.:173792-67-1
- H-Gly-OBzl.HCl
Catalog No.:BCC2949
CAS No.:1738-68-7
Antioxidant, antilipidemic and antidiabetic effects of ficusin with their effects on GLUT4 translocation and PPARγ expression in type 2 diabetic rats.
Chem. Biol. Interact.,2016,256:85-93.
In this study, the antioxidant, antilipidemic and antidiabetic effects of ficusin isolated from Ficus carica leaves and their effects on GLUT4 translocation and PPARγ expression were evaluated in HFD-STZ induced type 2 diabetic rats. Ficusin (20 and 40 mg/kg b. wt.) lowered the levels of fasting blood glucose, plasma insulin and body weight gain, in HFD-STZ induced diabetic rats. Ficusin Also significantly lowered the serum antioxidant enzymes (SOD, CAT and GPx) and lipids (TC, TG and FFA) levels to near normal. Ficusin significantly enhanced the PPARγ expression and improved the translocation and activation of GLUT4 in the adipose tissue. Molecular docking analysis exhibited promising interactions of GLUT4 and PPARγ into their active sites. This study suggests that ficusin improved the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitus.
Ficusin A,173429-83-9,Natural Products, buy Ficusin A , Ficusin A supplier , purchase Ficusin A , Ficusin A cost , Ficusin A manufacturer , order Ficusin A , high purity Ficusin A
