Eupaglehnin CCAS# 476630-49-6 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 476630-49-6 | SDF | Download SDF |
| PubChem ID | 131854185 | Appearance | Oil |
| Formula | C20H26O5 | M.Wt | 346.42 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(3aR,4R,6Z,10E,11aR)-6,10-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-4-yl] (Z)-2-(hydroxymethyl)but-2-enoate | ||
| SMILES | CC=C(CO)C(=O)OC1CC(=CCCC(=CC2C1C(=C)C(=O)O2)C)C | ||
| Standard InChIKey | LQAWDKQOLJURMN-VJQSGOAOSA-N | ||
| Standard InChI | InChI=1S/C20H26O5/c1-5-15(11-21)20(23)25-17-10-13(3)8-6-7-12(2)9-16-18(17)14(4)19(22)24-16/h5,8-9,16-18,21H,4,6-7,10-11H2,1-3H3/b12-9+,13-8-,15-5-/t16-,17-,18+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Eupatorium glehni.
| Description | 1. Eupaglehnin C shows cytotoxic (2.19 mg/ml) against HeLa-S3. |
Eupaglehnin C Dilution Calculator
Eupaglehnin C Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.8867 mL | 14.4333 mL | 28.8667 mL | 57.7334 mL | 72.1667 mL |
| 5 mM | 0.5773 mL | 2.8867 mL | 5.7733 mL | 11.5467 mL | 14.4333 mL |
| 10 mM | 0.2887 mL | 1.4433 mL | 2.8867 mL | 5.7733 mL | 7.2167 mL |
| 50 mM | 0.0577 mL | 0.2887 mL | 0.5773 mL | 1.1547 mL | 1.4433 mL |
| 100 mM | 0.0289 mL | 0.1443 mL | 0.2887 mL | 0.5773 mL | 0.7217 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- VO-Ohpic trihydrate
Catalog No.:BCC2043
CAS No.:476310-60-8
- Boldine
Catalog No.:BCN5534
CAS No.:476-70-0
- Corydine
Catalog No.:BCN2669
CAS No.:476-69-7
- Ellagic acid
Catalog No.:BCN5533
CAS No.:476-66-4
- Chelidonine
Catalog No.:BCN2463
CAS No.:476-32-4
- Lycorine
Catalog No.:BCN2409
CAS No.:476-28-8
- Xylotriose
Catalog No.:BCN8428
CAS No.:47592-59-6
- Isotretinoin
Catalog No.:BCC2284
CAS No.:4759-48-2
- MCL 0020
Catalog No.:BCC6025
CAS No.:475498-26-1
- NVP-AEW541
Catalog No.:BCC1180
CAS No.:475489-16-8
- NVP-ADW742
Catalog No.:BCC4553
CAS No.:475488-23-4
- Aleglitazar
Catalog No.:BCC1337
CAS No.:475479-34-6
New Products
- Lushanrubescensin H
Catalog No.:BCN3235
CAS No.:476640-22-9
- 6,9,10-Trihydroxy-7-megastigmen-3-one
Catalog No.:BCN1435
CAS No.:476682-97-0
- 3-(2-Benzothiazolylthio)propionic acid
Catalog No.:BCC8586
CAS No.:4767-00-4
- Boc-Tyr(2-Br-Z)-OH
Catalog No.:BCC3460
CAS No.:47689-67-8
- Lycorenine
Catalog No.:BCN2507
CAS No.:477-19-0
- Demecolcine
Catalog No.:BCC9223
CAS No.:477-30-5
- Samidin
Catalog No.:BCN6665
CAS No.:477-33-8
- Dehydrocostus lactone
Catalog No.:BCN5536
CAS No.:477-43-0
- Beta-Apopicropodophyllin
Catalog No.:BCC1388
CAS No.:477-52-1
- Podophyllotoxinone
Catalog No.:BCN8063
CAS No.:477-49-6
- Isotetrandrine
Catalog No.:BCN5538
CAS No.:477-57-6
- Isochondodendrine
Catalog No.:BCC9234
CAS No.:477-62-3
Seven germacranolides, eupaglehnins A, B, C, D, E, and F, and 2alpha-acetoxyepitulipinolide from Eupatorium glehni.
Chem Pharm Bull (Tokyo). 2002 Sep;50(9):1250-4.
We have been interested in biologically active terpenoids from Compositae9—14) and collected E. glehni6—8) in Tokushima and Hokkaido, Japan. From the ethyl acetate-soluble fraction of the methanol extract, we have found four new germacranolides with unsaturated esters at the 8-position, eupaglehnin A, eupaglehnin B, Eupaglehnin C, and eupaglehnin D, and two new chlorine atom-containing germacranolides, eupaglehnin E (5) and eupaglehnin F (6),13) as well as 2a-acetoxyepitulipinolide (7) for the first time from natural sources. In our attempt to find cytotoxic compounds, eupatoriopicrin (8) 24—29) was the most effective (1.40 mg/ml), followed by Eupaglehnin C (3) (2.19 mg/ml) against HeLa-S3. However, eupaglehnin E (5) and eupaglehnin F (6) did not show cytotoxic activity, which is understandable because they had no exomethylene group. In preliminary experiments, eupatoriopicrin (8) 24—26) also showed apoptotic activity against Ha-60 cell lines, the details of which will be published in due course.
Eupaglehnin C,476630-49-6,Natural Products, buy Eupaglehnin C , Eupaglehnin C supplier , purchase Eupaglehnin C , Eupaglehnin C cost , Eupaglehnin C manufacturer , order Eupaglehnin C , high purity Eupaglehnin C
