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Clematiunicinoside E

CAS# 916649-92-8

Clematiunicinoside E

Catalog No. BCN7809----Order now to get a substantial discount!

Product Name & Size Price Stock
Clematiunicinoside E:5mg Please Inquire In Stock
Clematiunicinoside E:10mg Please Inquire In Stock
Clematiunicinoside E:20mg Please Inquire In Stock
Clematiunicinoside E:50mg Please Inquire In Stock

Quality Control of Clematiunicinoside E

Number of papers citing our products

Chemical structure

Clematiunicinoside E

3D structure

Chemical Properties of Clematiunicinoside E

Cas No. 916649-92-8 SDF Download SDF
PubChem ID 11994185 Appearance Powder
Formula C76H124O39 M.Wt 1661.79
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[(2S,3R,4S,5S)-3-[(2S,3R,4R,5S,6S)-4-[(2S,3R,4S,5R)-5-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxyoxan-2-yl]oxy-3,5-dihydroxy-6-methyloxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
SMILES CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OCC3C(C(C(C(O3)OC(=O)C45CCC(CC4C6=CCC7C8(CCC(C(C8CCC7(C6(CC5)C)C)(C)C)OC9C(C(C(CO9)O)O)OC1C(C(C(C(O1)C)O)OC1C(C(C(CO1)OC1C(C(C(C(O1)CO)OC1C(C(C(C(O1)CO)O)O)O)O)O)O)O)O)C)(C)C)O)O)O)CO)O)O)O
Standard InChIKey FICAKDVNAHFTMY-JYHFIEJESA-N
Standard InChI InChI=1S/C76H124O39/c1-27-40(81)46(87)52(93)64(103-27)111-58-33(22-78)106-62(55(96)49(58)90)101-25-35-44(85)48(89)54(95)67(109-35)115-70(99)76-18-16-71(3,4)20-30(76)29-10-11-38-73(7)14-13-39(72(5,6)37(73)12-15-75(38,9)74(29,8)17-19-76)110-69-61(42(83)31(80)24-100-69)114-68-57(98)60(41(82)28(2)104-68)113-63-51(92)45(86)36(26-102-63)108-65-56(97)50(91)59(34(23-79)107-65)112-66-53(94)47(88)43(84)32(21-77)105-66/h10,27-28,30-69,77-98H,11-26H2,1-9H3/t27-,28-,30-,31-,32+,33+,34+,35+,36+,37-,38+,39-,40-,41-,42-,43+,44+,45+,46+,47-,48-,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63-,64-,65-,66-,67-,68-,69-,73-,74+,75+,76-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Clematiunicinoside E

The roots of Clematis uncinata.

Biological Activity of Clematiunicinoside E

DescriptionClematiunicinoside E is a natural product from Clematis uncinata.

Protocol of Clematiunicinoside E

Structure Identification
Chem Pharm Bull (Tokyo). 2014;62(1):35-44.

Triterpenoid saponins from the roots of Clematis uncinata.[Pubmed: 24152568]


METHODS AND RESULTS:
Eight new bisdesmosidic triterpenoid saponins, clematiunicinoside A, clematiunicinoside B, clematiunicinoside C, clematiunicinoside D,Clematiunicinoside E, clematiunicinoside F, clematiunicinoside G, clematiunicinoside H (1-8), along with eleven known ones (9-19), were isolated from the roots of Clematis uncinata. Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence.
CONCLUSIONS:
All the isolated saponins were tested for their cytotoxic activities on human caski cervical cancer (Caski) cells, and compounds 13, 17 and 19 exhibited inhibitory effect on Caski cells.

Clematiunicinoside E Dilution Calculator

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Clematiunicinoside E Molarity Calculator

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Preparing Stock Solutions of Clematiunicinoside E

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.6018 mL 3.0088 mL 6.0176 mL 12.0352 mL 15.044 mL
5 mM 0.1204 mL 0.6018 mL 1.2035 mL 2.407 mL 3.0088 mL
10 mM 0.0602 mL 0.3009 mL 0.6018 mL 1.2035 mL 1.5044 mL
50 mM 0.012 mL 0.0602 mL 0.1204 mL 0.2407 mL 0.3009 mL
100 mM 0.006 mL 0.0301 mL 0.0602 mL 0.1204 mL 0.1504 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Clematiunicinoside E

Triterpenoid saponins from the roots of Clematis uncinata.[Pubmed:24152568]

Chem Pharm Bull (Tokyo). 2014;62(1):35-44. Epub 2013 Oct 22.

Eight new bisdesmosidic triterpenoid saponins, clematiunicinosides A-H (1-8), along with eleven known ones (9-19), were isolated from the roots of Clematis uncinata. Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. All the isolated saponins were tested for their cytotoxic activities on human caski cervical cancer (Caski) cells, and compounds 13, 17 and 19 exhibited inhibitory effect on Caski cells.

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