Chlorahololide CCAS# 1007859-25-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1007859-25-7 | SDF | Download SDF |
| PubChem ID | 127045345 | Appearance | Powder |
| Formula | C33H36O9 | M.Wt | 576.64 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| SMILES | CC1=C2C(C3C(=C)C4CC4C3(C5C2(C6=C7C(C8CC8C7(C5)O)(C(C(=O)C6=C(C)C(=O)OC)O)C)OC1=O)C)OC(=O)C | ||
| Standard InChIKey | FUWHPWXSVUDXDS-XMJAEXKHSA-N | ||
| Standard InChI | InChI=1S/C33H36O9/c1-11-15-8-16(15)30(5)19-10-32(39)18-9-17(18)31(6)26(32)23(20(24(35)27(31)36)12(2)28(37)40-7)33(19)22(13(3)29(38)42-33)25(21(11)30)41-14(4)34/h15-19,21,25,27,36,39H,1,8-10H2,2-7H3/b20-12-/t15-,16-,17-,18+,19+,21-,25-,27+,30-,31+,32+,33-/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The whole plants of Chloranthus holostegius.
| Description | 1. Chlorahololide C is a potent and selective potassium channel blocker, it exerts potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with the IC(50) value of 3.6 +/- 10.1 mu M. |
| Targets | Potassium Channel |
Chlorahololide C Dilution Calculator
Chlorahololide C Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.7342 mL | 8.6709 mL | 17.3418 mL | 34.6837 mL | 43.3546 mL |
| 5 mM | 0.3468 mL | 1.7342 mL | 3.4684 mL | 6.9367 mL | 8.6709 mL |
| 10 mM | 0.1734 mL | 0.8671 mL | 1.7342 mL | 3.4684 mL | 4.3355 mL |
| 50 mM | 0.0347 mL | 0.1734 mL | 0.3468 mL | 0.6937 mL | 0.8671 mL |
| 100 mM | 0.0173 mL | 0.0867 mL | 0.1734 mL | 0.3468 mL | 0.4335 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- (R)-5-Hydroxy-1,7-diphenyl-3-heptanone
Catalog No.:BCN3591
CAS No.:100761-20-4
- Ganoderic acid M
Catalog No.:BCN2871
CAS No.:100761-17-9
- 1-O-Deacetylkhayanolide E
Catalog No.:BCN5823
CAS No.:1007387-95-2
- CH5132799
Catalog No.:BCC4991
CAS No.:1007207-67-1
- 3-(Hydroxymethyl)cyclopentanol
Catalog No.:BCN5822
CAS No.:1007125-14-5
- Deacetyl ganoderic acid F
Catalog No.:BCN2870
CAS No.:100665-44-9
- Ganoderenic acid D
Catalog No.:BCN2445
CAS No.:100665-43-8
- Ganoderenic acid C
Catalog No.:BCN3210
CAS No.:100665-42-7
- Ganoderenic acid B
Catalog No.:BCN7966
CAS No.:100665-41-6
- Ganoderenic acid A
Catalog No.:BCN3208
CAS No.:100665-40-5
- Desloratadine
Catalog No.:BCC4540
CAS No.:100643-71-8
- (-)-Epipinoresinol
Catalog No.:BCN3377
CAS No.:10061-38-8
New Products
- 4,4'-Bis(α,α-dimethylbenzyl)diphenylamine
Catalog No.:BCC8661
CAS No.:10081-67-1
- (RS)-CPP
Catalog No.:BCC6561
CAS No.:100828-16-8
- Piceatannol
Catalog No.:BCN5824
CAS No.:10083-24-6
- Panamycin 607
Catalog No.:BCN1813
CAS No.:100905-89-3
- AZD8055
Catalog No.:BCC3629
CAS No.:1009298-09-2
- AZD2014
Catalog No.:BCC3732
CAS No.:1009298-59-2
- Caulophyllumine A
Catalog No.:BCN7928
CAS No.:1009318-60-8
- Stachyose
Catalog No.:BCN2566
CAS No.:10094-58-3
- 2,2-Bis(hydroxymethyl)butyric acid
Catalog No.:BCC8495
CAS No.:10097-02-6
- Rotundine
Catalog No.:BCN5983
CAS No.:10097-84-4
- Ebrotidine
Catalog No.:BCC1542
CAS No.:100981-43-9
- Thiamet G
Catalog No.:BCC4864
CAS No.:1009816-48-1
Chlorahololides C–F: a new class of potent and selective potassium channel blockers from Chloranthus holostegius
Tetrahedron, 2008, 64(9):2027-2034.
Four unusually fused polycyclic sesquiterpenoid dimers, Chlorahololide C,chlorahololide D, chlorahololide E, chlorahololide F (1 - 4), were isolated from the whole plant of Chloranthus holostegius. Their structures and absolute configurations were established by spectroscopic methods, including 2D NMR and CD spectra. Chlorahololides C - F (1 - 4) exerted potent and selective inhibition on the delayed rectifier (I(K)) K(+) current with the IC(50) values of 3.6 +/- 10.1, 2.7 +/- 0.3, 27.5 +/- 5.1. and 57.5 +/- 6.1 mu M, respectively.
Chlorahololide C,1007859-25-7,Natural Products, buy Chlorahololide C , Chlorahololide C supplier , purchase Chlorahololide C , Chlorahololide C cost , Chlorahololide C manufacturer , order Chlorahololide C , high purity Chlorahololide C
