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Caulophyllumine A

CAS# 1009318-60-8

Caulophyllumine A

Catalog No. BCN7928----Order now to get a substantial discount!

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Caulophyllumine A:5mg Please Inquire In Stock
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Caulophyllumine A:50mg Please Inquire In Stock

Quality Control of Caulophyllumine A

Number of papers citing our products

Chemical structure

Caulophyllumine A

3D structure

Chemical Properties of Caulophyllumine A

Cas No. 1009318-60-8 SDF Download SDF
PubChem ID 101844612 Appearance Powder
Formula C15H21NO4 M.Wt 279.33
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name 1-(4-hydroxy-2,3-dimethoxyphenyl)-2-[(2S)-piperidin-2-yl]ethanone
SMILES COC1=C(C=CC(=C1OC)O)C(=O)CC2CCCCN2
Standard InChIKey MCMMIRWNWGZONI-JTQLQIEISA-N
Standard InChI InChI=1S/C15H21NO4/c1-19-14-11(6-7-12(17)15(14)20-2)13(18)9-10-5-3-4-8-16-10/h6-7,10,16-17H,3-5,8-9H2,1-2H3/t10-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Caulophyllumine A

The herbs of Cimicifuga heracleifolia

Biological Activity of Caulophyllumine A

DescriptionCaulophyllumine A is a natural product from Cimicifuga heracleifolia.

Protocol of Caulophyllumine A

Structure Identification
Phytochemistry. 2008 Feb;69(4):1037-42.

Alkaloids and saponins from blue cohosh.[Pubmed: 18048069 ]

Blue cohosh, Caulophyllum thalictroides (L.) Michx. (Berberidaceae), is used primarily to cure menstrual disturbances and to ease childbirth. Alkaloids and saponins are considered to be responsible for its pharmacological activity.
METHODS AND RESULTS:
A detailed phytochemical investigation of blue cohosh resulted in the isolation of 15 compounds belonging to the alkaloids and the triterpene saponins.
CONCLUSIONS:
The structures of two alkaloids, Caulophyllumine A (1) and caulophyllumine B (2) and a saponin, cauloside H (3) both previously unknown were determined by spectroscopic techniques, including by 1- and 2-D NMR as well as by chemical analysis.

Caulophyllumine A Dilution Calculator

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Caulophyllumine A Molarity Calculator

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Preparing Stock Solutions of Caulophyllumine A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.58 mL 17.9 mL 35.7999 mL 71.5999 mL 89.4999 mL
5 mM 0.716 mL 3.58 mL 7.16 mL 14.32 mL 17.9 mL
10 mM 0.358 mL 1.79 mL 3.58 mL 7.16 mL 8.95 mL
50 mM 0.0716 mL 0.358 mL 0.716 mL 1.432 mL 1.79 mL
100 mM 0.0358 mL 0.179 mL 0.358 mL 0.716 mL 0.895 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Caulophyllumine A

Alkaloids and saponins from blue cohosh.[Pubmed:18048069]

Phytochemistry. 2008 Feb;69(4):1037-42.

Blue cohosh, Caulophyllum thalictroides (L.) Michx. (Berberidaceae), is used primarily to cure menstrual disturbances and to ease childbirth. Alkaloids and saponins are considered to be responsible for its pharmacological activity. A detailed phytochemical investigation of blue cohosh resulted in the isolation of 15 compounds belonging to the alkaloids and the triterpene saponins. The structures of two alkaloids, caulophyllumines A (1) and B (2) and a saponin, cauloside H (3) both previously unknown were determined by spectroscopic techniques, including by 1- and 2-D NMR as well as by chemical analysis.

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