Axillarine

CAS# 19637-66-2

Axillarine

Catalog No. BCN2059----Order now to get a substantial discount!

Product Name & Size Price Stock
Axillarine:5mg Please Inquire In Stock
Axillarine:10mg Please Inquire In Stock
Axillarine:20mg Please Inquire In Stock
Axillarine:50mg Please Inquire In Stock

Quality Control of Axillarine

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Chemical structure

Axillarine

3D structure

Chemical Properties of Axillarine

Cas No. 19637-66-2 SDF Download SDF
PubChem ID 309285 Appearance Cryst.
Formula C18H27NO7 M.Wt 369.41
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC(C)C1C(C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C(C)O)O)O
Standard InChIKey JGQRXNDIMGIXDT-UHFFFAOYSA-N
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Protocol of Axillarine

Structure Identification
Phytochemistry,1985,24,(2):376–378.

Pyrrolizidine alkaloids from seeds of Crotalaria scassellatii[Reference: WebLink]


METHODS AND RESULTS:
Three pyrrolizidine alkaloids were isolated from the seeds of Crotalaria scassellatii.
CONCLUSIONS:
Axillaridine and Axillarine were the two major alkaloids whereas the third minor alkaloid was a new compound. Its structure was determined as desoxyAxillarine.

Axillarine Dilution Calculator

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Axillarine Molarity Calculator

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Preparing Stock Solutions of Axillarine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.707 mL 13.5351 mL 27.0702 mL 54.1404 mL 67.6755 mL
5 mM 0.5414 mL 2.707 mL 5.414 mL 10.8281 mL 13.5351 mL
10 mM 0.2707 mL 1.3535 mL 2.707 mL 5.414 mL 6.7675 mL
50 mM 0.0541 mL 0.2707 mL 0.5414 mL 1.0828 mL 1.3535 mL
100 mM 0.0271 mL 0.1354 mL 0.2707 mL 0.5414 mL 0.6768 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Axillarine

Generation and characterization of monoclonal antibodies against the pyrrolizidine alkaloid retrorsine.[Pubmed:9581524]

Planta Med. 1998 Apr;64(3):259-63.

Monoclonal antibodies against retrorsine were established using a retrorsine-hemisuccinate::bovine-thyroglobuline conjugate as antigen for immunization. In competitive enzyme-linked immunoassays the specificity of the obtained antibodies was tested with 20 different pyrrolizidine alkaloids. Among these the alkaloids acetylgynuramine, gynuramine, integerrimine, neoplatyphylline, platyphylline, rosmarinine, senecionine, and seneciphylline were able to bind the antibody. There was no cross-reactivity with the alkaloids senkirkine, angeloyl-heliotridine, heliotridine, Axillarine, anacrotine, monocrotaline, madurensine, otosenine, retronecine, tussilagine, triangularine, and jacoline as well as with seneciphylline N-oxide. From this antigen spectrum it can be concluded that besides the necic structure itself the dominant and discriminative epitope consists of the exocyclic ethylidene group of the various diesters.

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