Amycomycin

CAS# 344362-08-9

Amycomycin

Catalog No. BCN1824----Order now to get a substantial discount!

Product Name & Size Price Stock
Amycomycin:5mg Please Inquire In Stock
Amycomycin:10mg Please Inquire In Stock
Amycomycin:20mg Please Inquire In Stock
Amycomycin:50mg Please Inquire In Stock

Quality Control of Amycomycin

Number of papers citing our products

Chemical structure

Amycomycin

3D structure

Chemical Properties of Amycomycin

Cas No. 344362-08-9 SDF Download SDF
PubChem ID 54708635 Appearance Powder
Formula C65H115NO18 M.Wt 1198.62
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (3E,5Z)-1-methyl-5-(2-methylpropylidene)-3-[(2E,20E,24E)-1,5,7,11,13,17,19,26,27,29,31,35,37,41,43-pentadecahydroxy-2,10,12,18,20,22,24,32,40,42,44-undecamethyl-23-oxopentatetraconta-2,20,24-trienylidene]pyrrolidine-2,4-dione
SMILES CC(C)C=C1C(=O)C(=C(C(=CCC(CC(CCC(C)C(C(C)C(CCCC(C(C)C(C(=CC(C)C(=O)C(=CC(C(CC(CC(C(C)CCC(CC(CCC(C)C(C(C)C(C(C)C)O)O)O)O)O)O)O)O)C)C)O)O)O)O)O)O)C)O)C(=O)N1C
Standard InChIKey VNFAKMBHDHVYLZ-HSTNYJNZSA-N
Standard InChI InChI=1S/C65H115NO18/c1-34(2)27-51-64(83)57(65(84)66(51)15)63(82)39(8)22-26-49(70)31-47(68)24-20-37(6)60(79)43(12)52(72)17-16-18-53(73)44(13)62(81)41(10)28-40(9)59(78)42(11)29-55(75)56(76)33-50(71)32-54(74)36(5)19-23-46(67)30-48(69)25-21-38(7)61(80)45(14)58(77)35(3)4/h22,27-29,34-38,40,43-50,52-56,58,60-62,67-77,79-82H,16-21,23-26,30-33H2,1-15H3/b39-22+,41-28+,42-29+,51-27-,63-57+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Amycomycin

The Amycolatopsis sp.

Biological Activity of Amycomycin

Description1. Amycomycin is active against gram-positive bacteria , it is useful as an antibiotic.
TargetsAntifection

Amycomycin Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Amycomycin Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Amycomycin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.8343 mL 4.1715 mL 8.3429 mL 16.6859 mL 20.8573 mL
5 mM 0.1669 mL 0.8343 mL 1.6686 mL 3.3372 mL 4.1715 mL
10 mM 0.0834 mL 0.4171 mL 0.8343 mL 1.6686 mL 2.0857 mL
50 mM 0.0167 mL 0.0834 mL 0.1669 mL 0.3337 mL 0.4171 mL
100 mM 0.0083 mL 0.0417 mL 0.0834 mL 0.1669 mL 0.2086 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Amycomycin

Angucyclines from an insect-derived actinobacterium Amycolatopsis sp. HCa1 and their cytotoxic activity.[Pubmed:23131338]

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7490-3.

One new angucyclinone derivative, Amycomycin A (1), and one new angucycline, Amycomycin B (2), along with 5 known compounds (3-7), were isolated from an actinobacterium Amycolatopsis sp. HCa1 associated with the grasshopper, Oxya chinensis. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR spectra. Compounds 1-7 were tested in vitro for their cytotoxic effects on five cell lines including human gastric adenocarcinoma cell line (BGC823), human hepatocarcinoma cell line (HepG2), human melanoma cell line (A375), human oral squamous carcinoma cell line (KB), and ghost cell line (Ghost-R5X4). Cell viability assays showed that compound 7 was active in four cell lines with IC(50) values less than 18.0 muM except in KB showing no activity up to 100 muM.

Keywords:

Amycomycin,344362-08-9,Natural Products, buy Amycomycin , Amycomycin supplier , purchase Amycomycin , Amycomycin cost , Amycomycin manufacturer , order Amycomycin , high purity Amycomycin

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: